Protein Alignment CG8850 and slc6a13

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001072913.1
• Gene: slc6a13 / 780375
• XenbaseID: XB-GENE-5947897
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 521
• Identity: 199/521 - (38%)
• Similarity: 297/521 - (57%)
• Gaps: 13/521 - (2%)

  Fly    56 QRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQF 120
            :|.||:..|||:.|.....:|||||||||::..:||||||.|||:|.|...|.||::||..:||:
 Frog    36 ERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQY 100

  Fly   121 SSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-K 183
            :|:|.:.|: .:.|:..||.|.......|...||..::|..:.||..||:..|||..|...|. :
 Frog   101 TSQGGVTAWRKICPLFEGIGYSSQVIVMLLNCYYIVVLAWALFYLFNSFTSELPWASCGHSWNTE 165

  Fly   184 SCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILS 248
            :|:......:..:..:.|.||...|:.:.|||..:.:|:  :|...|:|.||||..|:|....:.
 Frog   166 NCLDFYKGNSTHNVTLNGTSSVIEFWERRVLRISDGIDN--IGGLHWELALCLLLAWIICYFCIW 228

  Fly   249 KGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFS 313
            ||::|:||..||.|.|||:::||||||.|:||||..||.::|.|..|:|.:|.||..|.||:|||
 Frog   229 KGVKSTGKVVYFTATFPYLMLIVLLIRGVSLPGALTGIQFYLYPDLSRLQDPQVWMDAGTQIFFS 293

  Fly   314 LAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKG 378
            .|||.|.|....|:|.:|.|.::|.:.:..::|.||.:||..||.|||.:|.|... .||.|.:.
 Frog   294 YAICLGCLTALGSYNKYNNNCYRDCVALCFLNSGTSFVAGFAIFSILGFMAEEQGV-HISDVAES 357

  Fly   379 GAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHL-----PHW 438
            |.|||||:||.|::...:.| |:|..||||:::||:.|......::|..|.|.:..:     ...
 Frog   358 GPGLAFIAYPRAVSMMPFSP-LWACFFFFMVILLGLDSQFVCVESLVTAVVDMYPTIFRKKNRRE 421

  Fly   439 LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIYGVKRICSDIEF 502
            ||.:..|:|.||.||:.:|.||.:|..|.|:|..:.:.|: :||.|.|.|||:||.......:|.
 Frog   422 LLILGVSMISFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFETLCVGWVYGADNFYDKVEH 486

  Fly   503 MLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTY-RGVQYPPVYYMAGWIIWGLGVLQLPF 566
            |:..:.:...:.||..|.|.:.....::.|..|.|||| :...||......||::....::.:|.
 Frog   487 MIGYRPTGIIKYCWLFVTPAVCMATFLFSLVKYTPLTYNKHYVYPWWGDAIGWLLALSSMVCIPL 551

  Fly   567 W 567
            |
 Frog   552 W 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	186/481 (39%)
slc6a13	NP_001072913.1	SLC5-6-like_sbd	37..579	CDD:444915	199/520 (38%)