Protein Alignment CG8850 and Slc6a21

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_006541333.1
• Gene: Slc6a21 / 76713
• MGIID: 1923963
• Length: 749
• Species: Mus musculus
• Alignment Length: 675
• Identity: 162/675 - (24%)
• Similarity: 291/675 - (43%)
• Gaps: 146/675 - (21%)

  Fly    61 SRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGC 125
            ::..|.:...:|.|:|||:.||||::..:||||:||:.|.|:|||:|.|:.|:|::|||:.....
Mouse    52 AKKTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYFILLLLLGIPLMYMEMVIGQWLRMDN 116

  Fly   126 IRAFD-MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYC-LVE-----WGK 183
            |:|:. :.|.:.|:.|..:.:..|...|.:.:::.::.||..||...|||..| |||     .|.
Mouse   117 IQAWKYLVPWLSGVGYSNILACVLVVLYNSALVSWSLFYLGQSFDYPLPWQNCPLVENLSMVAGN 181

  Fly   184 SCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILS 248
            :|:.:              ...:.|:..|:|:....::: |:.....::.|||.|||:.:...:.
Mouse   182 TCLWS--------------EPHQYFWYHTLLQASNQMEE-GIEVLVLNVTLCLFATWIFLYVTMV 231

  Fly   249 KGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGA-----WQGIVYFLKPQWSQLLNPHVWYAAIT 308
            ..|:.|.....|..||..|:::...||.:.|.|:     |:.:...|    |.|.:...|..|..
Mouse   232 TRIKISVLMMIFSILFSNVLLLCFFIRTLFLNGSVRASLWRLVTIEL----SILSSLDAWRQAGG 292

  Fly   309 QMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTK--- 370
            .:.:||.:..||::.::::....:|..|....:..::..||:|:..:||.::|   |.|.|.
Mouse   293 HVLYSLGLGMGTIITFSTYQPRGENYIKWASFVAMVNLATSLLSSFVIFLVMG---FWTTTSGTM 354

  Fly   371 --------------------------DI--------------------SQV-------------- 375
                                      ||                    |||
Mouse   355 CIKRSVSNLINLIANGVLPKAAWPPGDIIHKPPLEYLAWINQLPNNLKSQVIHQTLPCSILIQKE 419

  Fly   376 -VKGGAGLAFISYPEAIAKFKYLP--QLFAVLFFFMLLVLGIGSNIGMASAVVNVVK---DRFTH 434
             :..|.||:::::.:||:.|   |  ..:|::||..|.::|:|:.:.:...:|..::   ..|..
Mouse   420 KIMEGPGLSYVAFSQAISLF---PGSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPLQKSISTFAK 481

  Fly   435 LPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSD 499
            .|: |:.|...:.|||..||:.:..|.:|:.|.|......:.:::.:.:.|::.|:||:||..::
Mouse   482 HPN-LVQVLVCLGGFLGSLVFSSRPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRFRAE 545

  Fly   500 IEFMLNVKTSFYW---RICWAIVA-PGLMFLVLVYMLFSYEPLTYRG--------------VQYP 546
            :...|.   |..|   ...|:.|. |.|:.|:.:|.|..|    |.|              |:.|
Mouse   546 VFGQLG---SLVWSPFTFLWSYVTLPTLLVLLTIYFLNLY----YSGSPYYVSWNDSMSHEVKQP 603

  Fly   547 PVYYMAGWIIWGLGVLQL---------PFWAL--VTIYQQPGKTFGSKFGLAMQPTANWGPLQTQ 600
            ......||:.: |.||.|         .:|.|  ..|.:...|...||..:.:.......|:...
Mouse   604 YKKIPLGWVTF-LSVLALLPILVYPLQHWWYLDDPNICETLEKPLSSKKTVTVPNRVTQWPVHPM 667

  Fly   601 KFEAYIIHRKREADF--KSPRGGYL 623
            :........|.:|.|  |||...:|
Mouse   668 RKLTLRNQEKSKALFQSKSPPENFL 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	136/555 (25%)
Slc6a21	XP_006541333.1	SLC5-6-like_sbd	48..622	CDD:382020	148/603 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920