Protein Alignment CG8850 and SLC6A7

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 224/642 - (34%)
• Similarity: 348/642 - (54%)
• Gaps: 62/642 - (9%)

  Fly    14 MQGAQGSREGHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLG 78
            |:..||:....|.:.|.:.|.  |.:|:     .:.:.:.:..|..|:..::||.|||...||||
Human    82 MKKLQGAHLRKPVTPDLLMTP--SDQGD-----VDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLG 139

  Fly    79 NVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQV 143
            ||||||:.|..|||||||:||.::|.:.|.|:::||:.:|||||.|.:..:.::|:.:|.....:
Human   140 NVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAML 204

  Fly   144 YSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-KSC----VATGATAANDSSIVQGVS 203
            ....|...||..|:|..:.||.||.:..|||.:|...|. :.|    |:.....|...::...||
Human   205 LIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVS 269

  Fly   204 SAELFFTQT----------------------VLREPESLDD------------NGLGTPS---WD 231
            .:|.:::||                      .|.:|...::            .|:|:|.   |:
Human   270 PSEEYWSQTHTEAEEEGRRGRVVSNSYPQVIFLPQPPKAEEGVSRYVLHIQGSQGIGSPGEIRWN 334

  Fly   232 LVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQ 296
            |.||||..|||:...:.||::||||..||.|.|||:|:::||:|.|||||||:||.::|.||:..
Human   335 LCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHH 399

  Fly   297 LLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILG 361
            ||:..||..|..|:|:||.:.||.|:.:||:|.|::|:::|..|:|..:::||||||..||.:||
Human   400 LLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLG 464

  Fly   362 NLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVN 426
            .::.|... .:.||.|.|.||||:.||:|:......| .::.|||||||.||:.|.......:|.
Human   465 YMSQELGV-PVDQVAKAGPGLAFVVYPQAMTMLPLSP-FWSFLFFFMLLTLGLDSQFAFLETIVT 527

  Fly   427 VVKDRFTHLPHWLLAVSASIIGFLC------GLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELL 485
            .|.|.|   |::|....|...|.:|      ||:..|.||.:.|.|:|.|..:|..:|:.|...|
Human   528 AVTDEF---PYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCL 589

  Fly   486 AVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYY 550
            ||..:||::|.|.||..||..|...|:|.||..::|..:..::||.:..|:|..|...::||...
Human   590 AVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAE 654

  Fly   551 MAGWIIWGLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQPTANWGP-LQTQKFEAYI 606
            :.|.::..|..|.:|...||.:.::.|..: .:...|.:|..:||| |:..:...|:
Human   655 LLGILMGLLSCLMIPAGMLVAVLREEGSLW-ERLQQASRPAMDWGPSLEENRTGMYV 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	196/521 (38%)
SLC6A7	XP_016865256.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920