Protein Alignment CG8850 and Slc6a17

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001028251.1
• Gene: Slc6a17 / 613226
• RGDID: 1587185
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 187/645 - (28%)
• Similarity: 305/645 - (47%)
• Gaps: 123/645 - (19%)

  Fly     1 MDDDAEYQKLRRNMQGAQGSREGHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVE 65
            :::..:|::...|:.|..|.::              ....|||    :||     .|..|:..::
  Rat    27 LEEPVDYKQSVLNVAGETGGKQ--------------KVAEEEL----DAE-----DRPAWNSKLQ 68

  Fly    66 FLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFD 130
            ::.:.|..||||||:||||::..:|||||:|:||:::|::||.|:::||:.:||...||.|..:.
  Rat    69 YILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWH 133

  Fly   131 -MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGKSCVATGATAAN 194
             :.|.:.||.:...........||..|:..::.|...||...|||:.|.|      :..|..|..
  Rat   134 YVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPV------IRNGTVAVV 192

  Fly   195 DSSIVQGVSSAELFFTQTVLREPESLD-DNGL---GTPSWDLVLCLLATWVIIGTILSKGIRSSG 255
            :....:  |||..:|...     |:|| .|.:   |..:|.:.:|||..|.|:|..:.|||:|||
  Rat   193 EPECEK--SSATTYFWYR-----EALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSG 250

  Fly   256 KASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGT 320
            |..||.:|||||::...|:|.:.|.||..||::...|:..::|:|.||..|.||:||:|.:.||.
  Rat   251 KVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGG 315

  Fly   321 LVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETN----------------- 368
            ::.::|:|..:.|.|.|..:::.|:..||:||..::|.:||   |:.|
  Rat   316 VIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLG---FKANIMNEKCVVENAEKILGY 377

  Fly   369 ---------------------TKDISQV------VK----------------------GGAGLAF 384
                                 |||.|::      ||                      .|.||||
  Rat   378 LNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAF 442

  Fly   385 ISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLLAVSASIIGF 449
            |::.||:..|...| .::|:||.||:.||:||.||..:.:...:.|.| .:|..:..|...:..|
  Rat   443 IAFTEAMTHFPASP-FWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF-KVPKEMFTVGCCVFAF 505

  Fly   450 LCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRI 514
            ..||:::...|.:.:.:.|.|..|....|:.|.|.:||.||||.|:...::..||..:...::..
  Rat   506 FVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFY 570

  Fly   515 CWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLG--VLQLPFWALVTI 572
            .|..|:|      |...:.:...:...||. ||.|  :.||.....  .|..|.||:..:
  Rat   571 MWKFVSP------LCMAVLTTASIIQLGVS-PPGY--SAWIKEEAAERYLYFPNWAMALL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	166/544 (31%)
Slc6a17	NP_001028251.1	SLC6sbd_NTT4	60..648	CDD:271403	178/589 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820