DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8850 and si:ch211-283g2.1

DIOPT Version :9

Sequence 1:	NP_725122.2	Gene:	CG8850 / 36331	FlyBaseID:	FBgn0033708	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_017211707.1	Gene:	si:ch211-283g2.1 / 569007	ZFINID:	ZDB-GENE-060531-57	Length:	581	Species:	Danio rerio

Alignment Length:	552	Identity:	200/552 - (36%)
Similarity:	310/552 - (56%)	Gaps:	24/552 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 AESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYL 113
            |..|.:| |..|||.:||..:.|..:|||||:||||::...:||||||:||:::|:::|.|:.::
Zfish     2 AAKEEAG-RPTWSRQIEFTLAGIGCAVGLGNIWRFPYLCYRSGGGAFLLPYLLMLVVLGIPLLHM 65

  Fly   114 EVIIGQFSSRGCIRAFDMA-PIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYC 177
            |:.:||:..||.:.|...| |:.:|:....|..:.:..|||..|:...:.|:.:||...|.|..|
Zfish    66 ELTLGQYLRRGPVLALAKACPLFKGVGMATVAISFIMCTYYNIIITWALYYMFSSFRSELLWQNC 130

  Fly   178 LVEWGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVI 242
            ...|.........|.::.||     ::::.||...||.....:::.  ||..|:|.|.||..|::
Zfish   131 NNTWNTVNCTDQVTNSSSSS-----TASQQFFNYKVLERTSGVEET--GTLRWELFLLLLLAWIL 188

  Fly   243 IGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAI 307
            :...:.||::|:||..||.|||||||::.|||..|.||||..||.:|:.|:|.:|||..||..|.
Zfish   189 VYLCIFKGVKSTGKVVYFTALFPYVILLALLINNVQLPGALDGIKFFIIPEWDKLLNVQVWINAA 253

  Fly   308 TQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDI 372
            .|:|.|:.|.||:|:..||:|::|.||.||.:.|...:|||||.||.:||...|.::...|. .:
Zfish   254 AQIFNSIGIGFGSLMAMASYNNYNNNVLKDTLAIAITNSLTSIFAGFVIFSAFGYMSHLQNV-PV 317

  Fly   373 SQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFT---- 433
            |::...|.||..:.||:|.......| |:|.|||||||.||:.|...|...:|..:.|.::
Zfish   318 SEIAVDGPGLVLVVYPQAFVTMPVAP-LWAFLFFFMLLCLGLDSQFAMVEVMVTSLLDSYSKPIL 381

  Fly   434 -HLPH----WLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGV 493
             ||..    .||...|:   ||.|:..:...|.:|..|:|.|......:.||..|::.|.|.|||
Zfish   382 KHLKRKEFLVLLVCGAA---FLLGIPNVMQVGIYVFQLMDHYTAIVSIMFLAFFEVVGVCWCYGV 443

  Fly   494 KRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWG 558
            ||:.|::..|...:.|.::||||.::.|.|:.::||:.:..::|..|....|||.....||:|..
Zfish   444 KRLSSNLVEMTGKRPSIFFRICWWVICPALITVILVFSVIQFKPARYEDYVYPPWAQGVGWLIAL 508

  Fly   559 LGVLQLPFWALVTIYQQPGKTFGSKFGLAMQP 590
            ..::.:|..|:.|::..|| :|..||..::.|
Zfish   509 ASIIWIPLAAVHTLWVLPG-SFTEKFKKSITP 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	179/483 (37%)
si:ch211-283g2.1	XP_017211707.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920