Protein Alignment CG8850 and Slc6a14

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_064433.3
• Gene: Slc6a14 / 56774
• MGIID: 1890216
• Length: 638
• Species: Mus musculus
• Alignment Length: 628
• Identity: 224/628 - (35%)
• Similarity: 340/628 - (54%)
• Gaps: 64/628 - (10%)

  Fly    41 EELTINCE----AESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVI 101
            |::|.:.|    .|::.:.:|..||:..::|.|.:..:||||||||||::...||||||||||.|
Mouse    16 EKVTASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAI 80

  Fly   102 VLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVA 166
            :|.|.|.|:::||..:|||:|.|.:..:.:.|:.:|:....|..:.....||..|:|.::.||.|
Mouse    81 MLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISVFVAIYYNVIIAYSLYYLFA 145

  Fly   167 SFSEVLPWTYCLVEWGKSC----------VATGA---------------TAANDSSIVQ-GVSSA 205
            ||..||||..|.....::|          |:.||               |..|.|.:.: |...:
Mouse   146 SFQSVLPWANCSSWADENCSRTPIVTGCNVSIGAGEMFMNISWVNTNNLTCLNGSEVFRPGQLPS 210

  Fly   206 ELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMI 270
            |.::.:..|:....:|:.|:..  |.|.||||..|:|:|..|.|||:||||..||.||||||:::
Mouse   211 EQYWDKVTLQRSSGMDETGVVV--WYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLL 273

  Fly   271 VLLIRAVTLPGAWQGIVYFLKPQ--WSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKN 333
            :||||..||.||.:||.|::..|  :::|....||..|.||:|:||::.:|.||..:|:|.||.|
Mouse   274 ILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNN 338

  Fly   334 VHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLP 398
            .:.|.||:...:.|||:.||..||.|||::| ..:.|::|||||.|..||||:||||:|:....|
Mouse   339 CYSDAIIVCLTNCLTSVFAGFAIFSILGHMA-HISGKEVSQVVKSGFDLAFIAYPEALAQLPAGP 402

  Fly   399 QLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRF------THLPHWLLAVSASIIGFLCGLVYMT 457
             .:::|||||||.||:.|.......:....:|.|      ..:|   :.:...:|.||.||:.:|
Mouse   403 -FWSILFFFMLLTLGLDSQFASIETITTTFQDLFPKAMKRMRVP---ITLGCCLILFLLGLLCVT 463

  Fly   458 PGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFY---WRICWAIV 519
            ..|.:.::|:|.:...:..|:.||.|:..:.||||..|...|||.|:..|...:   ||.||.::
Mouse   464 QAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVI 528

  Fly   520 APGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGW------IIWGLGVLQLPFWALVTIYQQPGK 578
            .|.|:..:||:.|..:....|..:.||......||      |||      :|..|::.|.|..|.
Mouse   529 TPILLSAILVWSLVKFHRPDYADIPYPDWGVALGWCMIIFCIIW------IPIMAIIKIVQAEGN 587

  Fly   579 TFGSKFGLAMQPTANWGP-LQTQKFEAY--IIHRKREADFKSP 618
            .. .:.....:|.:|||| |:..:.|.|  :....:|.|.:.|
Mouse   588 IL-QRIISCCRPASNWGPYLEKHRGERYRDMAEPAKETDHEIP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	194/510 (38%)
Slc6a14	NP_064433.3	SLC5-6-like_sbd	36..637	CDD:444915	220/608 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	618..638		3/12 (25%)