DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8850 and si:ch211-225b11.1

DIOPT Version :9

Sequence 1:	NP_725122.2	Gene:	CG8850 / 36331	FlyBaseID:	FBgn0033708	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001103931.1	Gene:	si:ch211-225b11.1 / 561694	ZFINID:	ZDB-GENE-060531-39	Length:	609	Species:	Danio rerio

Alignment Length:	567	Identity:	200/567 - (35%)
Similarity:	306/567 - (53%)	Gaps:	30/567 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLI 106
            |.|...:.|.:::..|:.|.|.:||:.:.|..:||||||||||::...:|||||||||:|:|.|.
Zfish    39 EATRLAKVEQQAAEPRETWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIMLFLC 103

  Fly   107 GRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSE 170
            |.|:.::|..:||::..|.:.|. .:.|:.:|:....|..:.:..|||..:|...:.||:.|||.
Zfish   104 GIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVISYVLCTYYNVLMTWALYYLLHSFSP 168

  Fly   171 VLPWTYCLVEWGKSCVATGATAANDSSIVQG-----VSSAELFFTQTVLREPESLDDNGLGTPSW 230
            .|||        :||..|..|.||.|:...|     .|:::.||...||.....::  ..|...|
Zfish   169 SLPW--------QSCNNTWNTVANCSTGFPGNATHLQSASQQFFDHKVLEMTSGIE--RAGGVRW 223

  Fly   231 DLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWS 295
            :|...|:..|.|:...:.||::|:||..||.|.|||.|:..||:..|.||||..||::||.|.||
Zfish   224 ELFGLLVLAWGIVYFCIFKGVKSTGKVVYFTATFPYFILFALLVNNVQLPGAKNGILFFLMPNWS 288

  Fly   296 QLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGIL 360
            :||...||..|..|:|.|:.|.||:::..||:|.:|.|:.:|..|::..:|.|||:||.:||..:
Zfish   289 KLLEVQVWVNAAAQIFNSIGISFGSMISMASYNKYNNNILRDTFIVSLANSATSIVAGFVIFSAI 353

  Fly   361 GNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLP--QLFAVLFFFMLLVLGIGSNIGMASA 423
            |.:|...|. .:..:...|.||.|:.|||.   |..:|  ||:|.|||.|||.||:.|...|...
Zfish   354 GYMAHIHNL-PVDDIATDGPGLVFVVYPEV---FSTMPVSQLWAPLFFIMLLCLGLDSQFAMVEV 414

  Fly   424 VVNVVKDRF------THLPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIA 482
            .|..:.|.|      ......|:.::....|||.|:.::|.||.:|..|:|.|......:.||..
Zfish   415 AVTFIMDGFGRKALKVFKRKELIVLAVCSFGFLLGIPHITRGGIYVFQLMDHYTAVVSLMFLAFF 479

  Fly   483 ELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTY-RGVQYP 546
            |:|||..|:||||:...:|.||..|.:.::||||..::|.|:..:|:..:..|.|..| :...||
Zfish   480 EVLAVTLIFGVKRLSVMVENMLGKKPNLFFRICWQYLSPMLVLGILISSIVQYTPARYGKSYTYP 544

  Fly   547 PVYYMAGWIIWGLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQPTAN 593
            ....:.||.|..:.::.:|..||..::...|... .:...::.||.:
Zfish   545 LWAELLGWFISLVSIIWIPLGALHELWTTEGSLL-QRLKKSITPTVD 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	182/487 (37%)
si:ch211-225b11.1	NP_001103931.1	SLC5-6-like_sbd	54..587	CDD:294310	195/547 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920