Protein Alignment CG8850 and slc6a11a

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001091857.1
• Gene: slc6a11a / 558960
• ZFINID: ZDB-GENE-030131-3729
• Length: 590
• Species: Danio rerio
• Alignment Length: 585
• Identity: 205/585 - (35%)
• Similarity: 313/585 - (53%)
• Gaps: 27/585 - (4%)

  Fly    56 QRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQF 120
            :|.||:..:|||.:.....:|||||||||::..:||||||.||||:.|:..|.|::.||..:||:
Zfish    20 ERGQWANKIEFLLTVAGAIIGLGNVWRFPYLCYKNGGGAFFIPYVLYLVTCGIPLFVLETSLGQY 84

  Fly   121 SSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-K 183
            :|:|.|..: .:.|:..|:.|.........:..|..|:|....||.:||:..|||..|...|. .
Zfish    85 TSQGGIMCWRKVCPLFEGMGYASQLIIVYGSITYIIIIAWAFLYLFSSFNVELPWASCNNPWNTD 149

  Fly   184 SC-VATGATAAND-SSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTI 246
            :| |.:|..:::: :|.:...||...|:...|||....::.  |||..|||.|.||..|:::...
Zfish   150 TCIVLSGRNSSSELASPLNSSSSVMEFWHHRVLRLSSGVEH--LGTVRWDLALILLLVWILVYFC 212

  Fly   247 LSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMF 311
            :.||::|:|||.||.|.||||::::||:|.||||||..||.|::.|..::|.:|.||..|.||:|
Zfish   213 IWKGVKSTGKAVYFTATFPYVMLLILLLRGVTLPGALNGIYYYMYPDLTRLADPQVWMDAGTQIF 277

  Fly   312 FSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVV 376
            :|.|||.|.|....|:|.:|.|.::|...:..::|.||.|.|..||.:||::|.|... |||.|.
Zfish   278 YSYAICLGYLSSLGSYNQYNNNCYRDSFYLCLLNSGTSFLGGFAIFSVLGHMAQEQGV-DISLVA 341

  Fly   377 KGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHL-----P 436
            :.|.||.||.||:|:.... |.|.:||.||.|:::||:.|......:::..|.|.|..:     .
Zfish   342 ESGPGLVFIVYPQAVTMLP-LSQFWAVCFFIMIILLGLDSQFVGLESIMTSVTDIFPTVLRRGFR 405

  Fly   437 HWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIYGVKRICSDI 500
            ..:|.:...::.:..||:.:|.||.:::.|.|.|.|:...|: ||..:.:|:||:||..|...:|
Zfish   406 REMLLLGICLVCYFMGLLMITEGGLYIIQLFDHYVCSGTTLLFLATCQSVAIGWVYGADRFYENI 470

  Fly   501 EFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRG-VQYPPVYYMAGWIIWGLGVLQL 564
            :.|:..|.....:.||..|.|.:.....::.|..|.||.:.. ..||...|..||.   |.|..|
Zfish   471 QDMIGYKPWPMVKYCWLYVTPSVCVGTFIFSLVKYSPLKFNNKYMYPWWAYGIGWF---LAVSSL 532

  Fly   565 PFWALVTIYQ-QPGK-TFGSKFGLAMQPTANWGPLQTQKFEAYIIHRKREADFKSPRGGYLFDNI 627
            ....:..||: ..|| ||..:..||..|..:....|......|.:....:.: |||      ||:
Zfish   533 SLIPINMIYKLHKGKGTFWERLQLACSPAEDLPQSQRPSAHHYTLSASTDRE-KSP------DNL 590

  Fly   628  627
            Zfish   591  590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	176/483 (36%)
slc6a11a	NP_001091857.1	SLC6sbd-TauT-like	21..560	CDD:271387	197/545 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820