Protein Alignment CG8850 and slc6a19a.1

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001091648.1
• Gene: slc6a19a.1 / 553256
• ZFINID: ZDB-GENE-070620-2
• Length: 629
• Species: Danio rerio
• Alignment Length: 644
• Identity: 189/644 - (29%)
• Similarity: 315/644 - (48%)
• Gaps: 100/644 - (15%)

  Fly    28 NDGISTVIYS-AEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENG 91
            |.|:...|.| :|.|:|      |.:.:|:|.:|....:::.:|:...||||||||||::...:|
Zfish     7 NPGLEQRIPSHSELEKL------ELQEAGERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHG 65

  Fly    92 GGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYAC 155
            ||||:||::|:|:|.|.|:.:||..|||....|.:..: .::|.:.|:....:.::.:...||..
Zfish    66 GGAFMIPFLILLVLEGVPLLHLEFAIGQRLRSGSVGVWRSISPYLTGVGIASMLASFIVGMYYNT 130

  Fly   156 IMALTIRYLVASFSEVLPWTYCLVEWGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESL 220
            |||..:.||..|..|.|||:.|.|...:    ||..:..:.|     |..:.|:.:..|....::
Zfish   131 IMAWVMWYLFNSLQEPLPWSQCPVNLNR----TGLVSECERS-----SPVDYFWYRETLNTSTAI 186

  Fly   221 DDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQG 285
            :|:  |...|.||||||..|..:.....:||.::|||.|..:..|||::.:.||||:||.|:..|
Zfish   187 EDS--GALQWWLVLCLLCAWTFLYICCIRGIETTGKAVYITSTLPYVVLTIFLIRALTLKGSVNG 249

  Fly   286 IVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSI 350
            |.:...|..::|:||..|..|..|:.||.::.||.|:.::|:|..:.|..:|.:.|:.|:.|||:
Zfish   250 IKFLFTPDVNELMNPSTWLDAGAQVLFSFSLAFGGLISFSSYNSVHNNCEQDAVTISIINGLTSV 314

  Fly   351 LAGCIIFGILGNLAFET-------------------------------------NTKDISQVVK- 377
            .:..:|:.|:|..|.|.                                     :..||.|.::
Zfish   315 YSATVIYSIIGFRATENYDICLDSNILSLLNAFDLPEGSITENNYTVALQQLNISRPDIIQELQL 379

  Fly   378 -------------GGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVK 429
                         .|.|||||.:.|||.|....| |::||||.||..||:.:..|....||..::
Zfish   380 KTCDMQTLLSEGVEGTGLAFIVFTEAITKMPVSP-LWSVLFFIMLFCLGLSTMFGNIEGVVVPLQ 443

  Fly   430 DRFTHLP-HWLLAVSAS---IIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWI 490
            | ...|| .|...|...   ::.||..||::...|.:.|.|.|.:..:...||:|:.||:||.::
Zfish   444 D-LNLLPKRWPKEVFTGLTCVVSFLTALVFVQSSGNYWLALFDGFAGSIPLLVIALCELIAVVYV 507

  Fly   491 YGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFS--YEPLTY------------- 540
            ||:.|...||:||:..|.:.:|:|.|..::|.::.::|::...:  .:.|||
Zfish   508 YGIDRFNEDIKFMVGHKPNIFWQISWRFLSPVILLVILIFYFITTVSKQLTYNVWDPQSADFPTL 572

  Fly   541 RGVQYPPVYYMAGWIIWGLGVLQLP-------FWALVTIYQQPGKTFGSKFGLAMQPTA 592
            :.|.||....:..:::.|:..|.:|       .|...|  ::..|:...|..:::...|
Zfish   573 KEVDYPNWISVVIFVLAGVPSLCIPGVAIGRALWRCCT--RRKHKSISEKQQMSVNTIA 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	165/529 (31%)
slc6a19a.1	NP_001091648.1	SLC5-6-like_sbd	31..611	CDD:444915	177/594 (30%)