Protein Alignment CG8850 and Slc6a16

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 610
• Identity: 150/610 - (24%)
• Similarity: 258/610 - (42%)
• Gaps: 107/610 - (17%)

  Fly    39 EGEELTINCEAE-SESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIV 102
            |..||......| ||....|..|:..||::.:.::..:....|.||....:..|..:|.|.|:::
Mouse   106 ESSELVNRMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFFIAYILM 170

  Fly   103 LLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVA 166
            ||.||.|:.:||:.:||.:.:.....: :::|...|:.|..|....:..||.....:..:.|:..
Mouse   171 LLGIGIPLLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWILFYMSH 235

  Fly   167 SFSEVLPWTYCLVEWGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWD 231
            .|..|:||..|.::         ..::|.....:..:|...|:.:..|:..:.::|.  |.||:.
Mouse   236 IFYFVVPWDQCPLQ---------RNSSNFDPECEQATSYTYFWYRKTLKASDRIEDG--GQPSFS 289

  Fly   232 LVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQ 296
            |.:.|..::.:|...|..||:|.||..:.|.|.||.|::..|||.:::.||..|:.:.|..:.:.
Mouse   290 LGMSLFLSFCLICAFLVNGIKSIGKVLFVLLLVPYSIIVCFLIRTLSMDGAEYGLKHLLILKVAS 354

  Fly   297 LLNPHVWYAAITQMFFSLAICFGTLVMYAS-FNDFNKNVHKDVIIITTIDSLTSILAGCIIFGIL 360
            :.:..:|..|..|:.|.:.:.||.:|..|| ..||| |...|..::.....:|.::....:..||
Mouse   355 ISDLTIWCHAGIQVLFDIGLGFGPIVSLASHVPDFN-NCMADAFLMALFKIITLLMTTPFLLSIL 418

  Fly   361 GNLAFET-------NTKDISQVVKGG-----------AGLAFISY-------------------P 388
            |..|..|       |.:.:.::|..|           :|....:|                   |
Mouse   419 GFWATTTTHHCCKKNQETLLRLVAQGILPPDAQPPDLSGNPTSNYNSWLSSLPPPLRSAVLSVVP 483

  Fly   389 EAIAKFKYL-----PQ-----------------LFAVLFFFMLLVLGIGSNIGMASAVVNVVKDR 431
            |...:.::|     |:                 .:.||||.:||.||:.||:......|..::|.
Mouse   484 ECSVQKQFLKIKDNPRFLFLIFTEVISLLPGSGFWIVLFFLLLLTLGLCSNLMFMLGNVLTLQDT 548

  Fly   432 F---THLPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGV 493
            |   ...|. ||.|..|:..|||||:::.|.|.:..:|:.........:::.|.|.|||.|.||.
Mouse   549 FPFCRRQPR-LLIVCVSMAMFLCGLIFIQPSGIYYFSLLSECWVAVPVIIIIICENLAVAWAYGA 612

  Fly   494 KRICSDIEFMLN--VKTSFYWRICWAIVAP----GLMFLVLVYMLFSYEPLTYRGVQYPPVYYMA 552
            .|..:|:..:|.  :.:...|  .|..::|    ||:..|.||:           |:.|.||:
Mouse   613 DRFLADMVALLGRPIFSGCGW--LWCYISPMVVLGLLTSVFVYL-----------VKGPLVYF-- 662

  Fly   553 GWIIWGLG-----VLQLPFWALVTI 572
               .|...     |...|.|:.:.|
Mouse   663 ---AWDSSTSKEVVRVFPEWSKILI 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	134/543 (25%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:444915	144/591 (24%)