Protein Alignment CG8850 and DAT

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 213/587 - (36%)
• Similarity: 310/587 - (52%)
• Gaps: 49/587 - (8%)

  Fly    54 SGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIG 118
            |.:|:.||..|:||.|.|..:|.|.||||||::..:|||||||:||.|:|::.|.|::|:|:.:|
  Fly    24 SDERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALG 88

  Fly   119 QFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEW- 181
            |.:.:|.|..:. :.|:.:||.|..|........||..|:|.::|:..|||:..||||.|...|
  Fly    89 QHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWN 153

  Fly   182 ---------------------------GKSCVATGATAANDSSI-------VQGV-SSAELFFTQ 211
                                       |...:....|..|.||:       |:|. |:|..:|.:
  Fly   154 TPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNR 218

  Fly   212 TVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRA 276
            .:|....|...:.||...||:.||||..::|....|.|||.:|||..:|.|||||.::::||||.
  Fly   219 YILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRG 283

  Fly   277 VTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIII 341
            :||||::.||.|:|.|.:|.:....||..|.||:||||...||.|:.|||:|.::.||:||.::.
  Fly   284 LTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLT 348

  Fly   342 TTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLP--QLFAVL 404
            :.|:|.||.:||.:||.:||.:|.....: |..|...|.||.|:.||.|||.   :|  ..:|::
  Fly   349 SFINSATSFIAGFVIFSVLGYMAHTLGVR-IEDVATEGPGLVFVVYPAAIAT---MPASTFWALI 409

  Fly   405 FFFMLLVLGIGSNIGMASAVVNVVKDRFTHLP--HWLLAVSASIIGFLCGLVYMTPGGQFVLNLV 467
            ||.|||.||:.|:.|.:.|::..:.|.|..:.  ..|.......:.|:.||...|.||.:..:|:
  Fly   410 FFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLL 474

  Fly   468 DFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYML 532
            |.|...:..||....|.:||.||||..|...||..|:......||::||..|||..:..:.||.|
  Fly   475 DRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGL 539

  Fly   533 FSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQPTANWGPL 597
            ..||||||....||......||.|.|..|:.:|..|:..:...|| :...:|.:...|   |...
  Fly   540 IGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPG-SLRQRFTILTTP---WRDQ 600

  Fly   598 QT 599
            |:
  Fly   601 QS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	189/514 (37%)
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	210/577 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440751
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850