Protein Alignment CG8850 and Ntl

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 584
• Identity: 210/584 - (35%)
• Similarity: 327/584 - (55%)
• Gaps: 28/584 - (4%)

  Fly    52 ESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVI 116
            |....|.||....||:.|.:..::|:|||||||::...:||.||||||:::::|.|.|::|:|::
  Fly    19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEIL 83

  Fly   117 IGQFSSRGCIRAFDMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEW 181
            ||||||.||...|.|.|:::|....||...|....||:.|::..||.:...|.:.:||..|...|
  Fly    84 IGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSW 148

  Fly   182 G-KSCV-ATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIG 244
            . ..|| |:.....|.|.:.:  :||:.||...|||  .|.|.:.||...|:.:..|:.||:||.
  Fly   149 NTDDCVTASDMGKQNSSDVFK--TSADEFFHLEVLR--ISTDISDLGGMVWEQLTALIITWIIIY 209

  Fly   245 TILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQ 309
            ..|.:||:|.||..||...|||:::.:||||..||||||:||.::|.|:|.:||:..||..|..|
  Fly   210 FCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQ 274

  Fly   310 MFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQ 374
            |||.:...:|.:|..|||:.|..|...|.::|.:|:..||:|||.::|.:||.|: |.:...:..
  Fly   275 MFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLS-EKSGIPVES 338

  Fly   375 VVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWL 439
            |..|||||||::||||||... :|||:|::|||||.:|||.|......|:::.:.|.:    :|:
  Fly   339 VATGGAGLAFVTYPEAIALLP-VPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEW----YWV 398

  Fly   440 LAVSASIIGFLC----GL--VYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICS 498
            .:....:....|    ||  :..|.||.|:|.|.|:|......:|:.:.|::.|.||||:|....
  Fly   399 RSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFML 463

  Fly   499 DIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQ 563
            |:||||..:.:.||||.|.:|.|.::..:|:..:.....:||..:.||....:.||......|:.
  Fly   464 DVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMW 528

  Fly   564 LPFWALVTIYQQPGKTFGSKFGLAMQPTANWGPLQTQ---KFEAYIIHRK-----READFKSPR 619
            :|.:....:.::.. |........::| .:|.|...|   ::||:...|:     .:.|.:|.:
  Fly   529 IPLYIFYIMIRKRA-TLCDSLKKRLKP-LDWTPADPQDRAEYEAFRRQRRMPGFMSDTDMESSK 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	190/481 (40%)
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	200/540 (37%)