DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8850 and NAAT1

DIOPT Version :9

Sequence 1:	NP_725122.2	Gene:	CG8850 / 36331	FlyBaseID:	FBgn0033708	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster

Alignment Length:	622	Identity:	284/622 - (45%)
Similarity:	413/622 - (66%)	Gaps:	32/622 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MQGAQGSREGHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLG 78
            ::|.|.|.....||.:|.:    :|...|.|   :|| :.:.:|..|..|:|||.|||::|||||
  Fly     3 LKGVQPSNGSSNGSGNGAT----NAASTEKT---DAE-KPTAERTNWGNGLEFLMSCISVSVGLG 59

  Fly    79 NVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQV 143
            |||||||.|.|||||||||||:|||.|||:|:||||:|:|||:|:|.::.:.:.|...|:.|||.
  Fly    60 NVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQA 124

  Fly   144 YSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGKSCV-----------ATGATAANDSS 197
            :.|....:||:.::|||:.||..||...|||:||..|| .:||           .||.:.||:|:
  Fly   125 FGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEW-TNCVNSRPQEYVDNLLTGVSLANESA 188

  Fly   198 -IVQGV----------SSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGI 251
             .:.|:          ||:||:|...|::|...:.| |:|.|.|.|.|.|...||:|..::.:|:
  Fly   189 RNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISD-GVGDPDWKLTLALFVAWVVIFLVIMRGV 252

  Fly   252 RSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAI 316
            :|||||:|||||||||::.|||||||||.||..||::||:|||.:||||.||..|:.|.|||||:
  Fly   253 KSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAV 317

  Fly   317 CFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAG 381
            ..|.::|:||:|.|:..:::|.:|:||:|:|||:|.|..||.||||||.....::|..||:.|.|
  Fly   318 GSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTG 382

  Fly   382 LAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLLAVSASI 446
            |||||||:||:||:.:||||:|||||||.||||||.:.:.|.:|.::.|:|....:|.:|::.|:
  Fly   383 LAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVALTTSV 447

  Fly   447 IGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFY 511
            .|||.||||:|||||::|.||||||.|::..:|||.||..:.|:||::..|.|||||.|.:.|.|
  Fly   448 CGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLY 512

  Fly   512 WRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFWALVTIYQQP 576
            ||:||:...|.:|.::.:|.:.:.||:.|..:.:|....:|||:::.:|..|.|.|.|..|.:.|
  Fly   513 WRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHP 577

  Fly   577 GKTFGSKFGLAMQPTANWGPLQTQKFEAYIIHRKREA 613
            ..|:......:::|:..|||...:....::|.:.::|
  Fly   578 QGTYWKSLKASLKPSDRWGPANPEIRREWVIFKNQKA 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	251/495 (51%)
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	251/494 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61415
OrthoDB	1	1.010	-	-		D14202at7147
OrthoFinder	1	1.000	-	-		FOG0008552
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.860