Protein Alignment CG8850 and Slc6a18

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_063141398.1
• Gene: Slc6a18 / 29323
• RGDID: 69352
• Length: 642
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 191/676 - (28%)
• Similarity: 306/676 - (45%)
• Gaps: 156/676 - (23%)

  Fly    38 AEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIV 102
            |.|.:..::.|.|      |.:|...:::|.|||..:|||||:||||::...:|||||||||.|.
  Rat     4 ASGMDPLVDIEDE------RPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIA 62

  Fly   103 LLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVA 166
            |:..|.|::|:|:.|||...||.|..: .::|.:.|:..|....:.|.:.||..|:...:.:.:.
  Rat    63 LVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLN 127

  Fly   167 SFSEVLPWTYCLVEWGKS-----CVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLG 226
            ||...|||:.|.::..::     |.::|..             :..::.||:   ..:.|.:..|
  Rat   128 SFQHPLPWSTCPLDLNRTGFVQECQSSGTV-------------SYFWYRQTL---NITSDISNTG 176

  Fly   227 TPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLK 291
            |..|.|.|||:|.|..:...:.:||.|:||..||.|||||:::.:.|||.:|||||.:|:.|...
  Rat   177 TIQWKLFLCLVACWTTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLTYLFT 241

  Fly   292 PQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCII 356
            |....|.||.||..|.||:||||::.||..:.:||:|....|..||.:.|..::|:||:.|...|
  Rat   242 PNMKILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSLYASITI 306

  Fly   357 FGILG-------------------------------NLAFETNTKDISQVVK------------- 377
            |.|:|                               :|||..:.::|..::.
  Rat   307 FSIMGFKASNDYGRCLDRTFLEHWNICWIIEHPVPSSLAFSCSCRNILSLINEFDFPELSISRDE 371

  Fly   378 ----------------------------------GGAGLAFISYPEAIAKFKYLP--QLFAVLFF 406
                                              .|.|||||.:.||:.   ::|  .:::||||
  Rat   372 YPSVLMYLNATQPERVARLPLKTCHLEDFLDKSASGPGLAFIVFTEAVL---HMPGASVWSVLFF 433

  Fly   407 FMLLVLGIGSNIGMASAVVNVVKDRF---THLPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVD 468
            .||..||:.|..|....|:..:.|..   ..:|...:......|.||..:.:....|.:.|.:.|
  Rat   434 GMLFTLGLSSMFGNMEGVITPLFDMGILPKGVPKETMTGVVCFICFLSAICFTLQSGSYWLEIFD 498

  Fly   469 FYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMF-LVLVYML 532
            .:..:...::.|..|::.|..:||:||.|.|||:|...:.|.||::.|.:|:|.|:| :.|.|::
  Rat   499 SFAASLNLIIFAFMEVVGVIHVYGIKRFCDDIEWMTGRRPSLYWQVTWRVVSPMLLFGIFLSYIV 563

  Fly   533 F-------------SYEPLTYRGVQ-YPPVYYMAGWI------------IW--GLGVLQLPFWAL 569
            .             .||....|..: ||      ||:            :|  |:.:.||.|.
  Rat   564 LLAQSSPSYKAWNPQYEHFPSREEKLYP------GWVQVTCVLLSFLPSLWVPGIALAQLLFQ-- 620

  Fly   570 VTIYQQPGKTFGSKFGLAMQPTANWG 595
               |:|..|  .:....|::|..:.|
  Rat   621 ---YRQRWK--NTHLESALKPQESRG 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	168/563 (30%)
Slc6a18	XP_063141398.1	None