Protein Alignment CG8850 and SLC6A16

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_011525161.2
• Gene: SLC6A16 / 28968
• HGNCID: 13622
• Length: 781
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 141/647 - (21%)
• Similarity: 260/647 - (40%)
• Gaps: 163/647 - (25%)

  Fly    41 EELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLL 105
            |::.:..:.|||....|..||...|::.:.:..|:....:|||.::.|.:||.:|...|:.:|.|
Human   169 EKVQMTEKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFL 233

  Fly   106 IGRPVYYLEVIIGQFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFS 169
            :|.|:.:||:..||...:|.:..:. :||.:.|:.|.......:...|:..:.:..|.|:..||.
Human   234 VGVPLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQ 298

  Fly   170 EVLPWTYCLVEWGKS-----CVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPS 229
            ..:||..|.:....|     |..|              :.:..|:.|..|:..:.::|.  |:|.
Human   299 FPVPWEKCPLTMNSSGFDPECERT--------------TPSIYFWYQQALKASDRIEDG--GSPV 347

  Fly   230 WDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQW 294
            :.|||.....|.::|..:..|::|:||.
Human   348 YSLVLPFFLCWCLVGAFMINGLKSTGKI------------------------------------- 375

  Fly   295 SQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGI 359
            |.:.|..||..|..|:..:..|..|::...||:...:.|...|..:::.|:.||.::.....|.:
Human   376 SDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCV 440

  Fly   360 LG-----------------------------------NLAF------------------------ 365
            ||                                   ||.:
Human   441 LGFWATVITHRCCERNAEILLKLINLGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLRE 505

  Fly   366 --ETNTKDISQVVKGGAG--LAFISYPEAIAKFKYLPQ--LFAVLFFFMLLVLGIGSNIGMASAV 424
              |.|.:  :|.:|...|  .||:|:.||::   :||.  .::.:||.|||.:|:.|.||:...:
Human   506 VTECNIE--TQFLKASEGPKFAFLSFVEAMS---FLPPSVFWSFIFFLMLLAMGLSSAIGIMQGI 565

  Fly   425 VNVVKDRFT----HLPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELL 485
            :..::|.|:    |..  ||.|...::.|:|||.:..|.|.:.:.|:..|...|..:|:.:.|.:
Human   566 ITPLQDTFSFFRKHTK--LLIVGVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETM 628

  Fly   486 AVGWIYGVKRICSDIEFMLN--VKTSFYWRICWAIVAPGLMFLVLVYML--FSYEPLTYRGVQ-- 544
            ||.|.||.:|..:|:..:|.  :...|.|  .|..:.|.::.::.|.|:  ...:|:||....
Human   629 AVSWAYGARRFLADLTILLGHPISPIFGW--LWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSS 691

  Fly   545 --------YPPVYYMAGWIIWGLGVLQLP-FWALVTIYQQPGKTFGSKFGLAMQPTANWGPL 597
                    |||...:....::.:.:|.:| ::....|::.|           .:|.:..||:
Human   692 TSKEVLRPYPPWALLLMITLFAIVILPIPAYFVYCRIHRIP-----------FRPKSGDGPM 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	122/550 (22%)
SLC6A16	XP_011525161.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820