Protein Alignment CG8850 and Slc6a17

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001280618.1
• Gene: Slc6a17 / 229706
• MGIID: 2442535
• Length: 727
• Species: Mus musculus
• Alignment Length: 645
• Identity: 186/645 - (28%)
• Similarity: 303/645 - (46%)
• Gaps: 123/645 - (19%)

  Fly     1 MDDDAEYQKLRRNMQGAQGSREGHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVE 65
            :::..:|::...|:.|..|.::              ....|||         .:..|..|:..::
Mouse    27 LEEPVDYKQSVLNVAGETGGKQ--------------KVAEEEL---------DTEDRPAWNSKLQ 68

  Fly    66 FLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFD 130
            ::.:.|..||||||:||||::..:|||||:|:||:::|::||.|:::||:.:||...||.|..:.
Mouse    69 YILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWH 133

  Fly   131 -MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGKSCVATGATAAN 194
             :.|.:.||.:...........||..|:..::.|...||...|||:.|.|      :..|..|..
Mouse   134 YVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPV------IRNGTVAVV 192

  Fly   195 DSSIVQGVSSAELFFTQTVLREPESLD-DNGL---GTPSWDLVLCLLATWVIIGTILSKGIRSSG 255
            :....:  |||..:|...     |:|| .|.:   |..:|.:.||||..|.|:|..:.|||:|||
Mouse   193 EPECEK--SSATTYFWYR-----EALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSG 250

  Fly   256 KASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGT 320
            |..||.:|||||::...|:|.:.|.||..||::...|:..::|:|.||..|.||:||:|.:.||.
Mouse   251 KVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGG 315

  Fly   321 LVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETN----------------- 368
            ::.::|:|..:.|.|.|..:::.|:..||:||..::|.:||   |:.|
Mouse   316 VIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLG---FKANIMNEKCVVENAEKILGY 377

  Fly   369 ---------------------TKDISQV------VK----------------------GGAGLAF 384
                                 |||.|::      ||                      .|.||||
Mouse   378 LNSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAF 442

  Fly   385 ISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLLAVSASIIGF 449
            |::.||:..|...| .::|:||.||:.||:||.||..:.:...:.|.| .:|..:..|...:..|
Mouse   443 IAFTEAMTHFPASP-FWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF-KVPKEMFTVGCCVFAF 505

  Fly   450 LCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRI 514
            ..||:::...|.:.:.:.|.|..|....|:.|.|.:||.||||.|:...::..||..:...::..
Mouse   506 FVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFY 570

  Fly   515 CWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLG--VLQLPFWALVTI 572
            .|..|:|      |...:.:...:...||. ||.|  :.||.....  .|..|.||:..:
Mouse   571 MWKFVSP------LCMAVLTTASIIQLGVS-PPGY--SAWIKEEAAERYLYFPNWAMALL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	167/544 (31%)
Slc6a17	NP_001280618.1	SLC6sbd_NTT4	60..648	CDD:271403	179/589 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727