Protein Alignment CG8850 and Slc6a2

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_033235.3
• Gene: Slc6a2 / 20538
• MGIID: 1270850
• Length: 617
• Species: Mus musculus
• Alignment Length: 536
• Identity: 199/536 - (37%)
• Similarity: 297/536 - (55%)
• Gaps: 16/536 - (2%)

  Fly    49 AESESSGQ-RDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYY 112
            |..:|..| |:.|.:.::||.|.:..:|.|.||||||::..:||||||||||.:.|::.|.|::|
Mouse    47 ASQDSDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFY 111

  Fly   113 LEVIIGQFSSRGCIRAFDMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYC 177
            :|:.:||::..|....:.:.|..:|:.|..:........||..|:|.::.||.|||:..||||.|
Mouse   112 MELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNC 176

  Fly   178 LVEWGK-SCV---ATGATAANDS---SIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLC 235
            ...|.. :|.   ...|:...|.   |..:...:|| |:.:.||...||...:.:|.|.|.|:||
Mouse   177 GHSWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAE-FYERGVLHLHESSGIHDIGLPQWQLLLC 240

  Fly   236 LLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNP 300
            |:...|::...|.||:::|||..:..|..||.::.|||:..||||||..||..:|...:.:|...
Mouse   241 LMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEA 305

  Fly   301 HVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAF 365
            .||..|.||:||||...||.|:.:||:|.|:.|.::|.::.:||:.:||.::|..||.|||.:|.
Mouse   306 TVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAH 370

  Fly   366 ETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKD 430
            | :..:|..|...||||.||.|||||:.... ...:|||||.|||.||:.|::|...||:..:.|
Mouse   371 E-HKVNIEDVATEGAGLVFILYPEAISTLSG-STFWAVLFFLMLLALGLDSSMGGMEAVITGLAD 433

  Fly   431 RFTHLPHW--LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGV 493
            .|..|...  |.....:|..||..|..:|.||.:||.|:|.:......|...:.|.:.|.|.|||
Mouse   434 DFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGV 498

  Fly   494 KRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWG 558
            .|..:||:.|:..|...|||:||..|:|..:..|:|..:.:::||||....|||   .|.|:.||
Mouse   499 DRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPP---WANWVGWG 560

  Fly   559 LGVLQLPFWALVTIYQ 574
            :.:..:.......||:
Mouse   561 IALSSMILVPAYVIYK 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	182/482 (38%)
Slc6a2	NP_033235.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SLC5-6-like_sbd	56..615	CDD:444915	196/527 (37%)