Protein Alignment CG8850 and mod-5

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_491095.3
• Gene: mod-5 / 171879
• WormBaseID: WBGene00003387
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 191/563 - (33%)
• Similarity: 301/563 - (53%)
• Gaps: 28/563 - (4%)

  Fly    53 SSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVII 117
            ||..||:|:..:|||.:.:..:|.|||:||||.:..::|||||||||.|:|::.|.|::|:|:::
 Worm    96 SSMVRDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFIMLMIGGLPMFYMELVL 160

  Fly   118 GQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEV----LPWTYC 177
            |||...||:..: .:.|:.|||.||..........:|..|:|..:.:.:.|.|::    :||..|
 Worm   161 GQFHRSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQAVYFAIVSLSKIWDSEVPWASC 225

  Fly   178 LVEWGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVI 242
            ...|.....:.........:.....:.:|.::...||...:|...:.||.....:.:||||.:::
 Worm   226 GNPWNTPRCSDDLNVTISRNGTPLTTPSEEYYLYKVLEVQKSTGFDDLGGVKTSMAVCLLAVFIM 290

  Fly   243 IGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAI 307
            :...|.||.:||||..:..|..||:|:.:||||.:.||||..|:.|::.|.:.:|.:|.||.||.
 Worm   291 VYFALWKGPQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGLYYYVTPDFEKLKDPAVWSAAA 355

  Fly   308 TQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDI 372
            ||:||||...||.|:..:|:||||.|.::|.:..:.|:..||..:||::|..||.::..|| |.|
 Worm   356 TQIFFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFFSGCVVFSTLGYMSLLTN-KPI 419

  Fly   373 SQVV-KGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLP 436
            ::|| :..|.|.||.||:|:|...| ...::.:||.||:.|||.|......|.:....|....|.
 Worm   420 NEVVGEHDASLIFIVYPQALATMDY-SCFWSFIFFVMLITLGIDSTFAGIEAFITGFCDESRFLS 483

  Fly   437 ---HWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICS 498
               .|.:.|...|..|| ....::.|||||:..:|.||.:...|.:...|::||.|.|||.:...
 Worm   484 KNRKWFVLVICIIYYFL-SFPAISYGGQFVIPFLDEYGVSLSVLFIVTCEMIAVCWFYGVDQFSK 547

  Fly   499 DIEFMLNVKTSFYWRICWAI--VAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGV 561
            ||..||......|||:||..  |...::|::.||. .|::|:......:|....:.||.:..|.|
 Worm   548 DIRAMLGFYPGIYWRVCWTCSPVFISVIFIMTVYN-SSFKPIQMASYTFPWWSVILGWFLRLLSV 611

  Fly   562 LQLPFWALV-------TIYQQ------PGKTFGSKFGLAMQPT 591
            |.:|.:|::       |:|::      |.:...|...||..||
 Worm   612 LAIPVFAIIYLLSGTGTLYERFRWAITPQQRRNSATSLAADPT 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	170/484 (35%)
mod-5	NP_491095.3	SLC6sbd_SERT-like	100..639	CDD:271388	183/542 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2944
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770