Protein Alignment CG8850 and Slc6a13

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_006237280.2
• Gene: Slc6a13 / 171163
• RGDID: 620788
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 197/545 - (36%)
• Similarity: 309/545 - (56%)
• Gaps: 34/545 - (6%)

  Fly    48 EAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYY 112
            :.|.:.:.:|:||:..:||:.|.....:|||||||||::..:||||||.|||:|.|...|.||::
  Rat    23 KVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFF 87

  Fly   113 LEVIIGQFSSRGCIRAF-DMAPIMR------GIAYGQVYSTALATTYYACIMALTIRYLVASFSE 170
            ||..:||::::|.|.|: .:.||..      ||.|......:|...||..::|..:.||.:||:.
  Rat    88 LETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTT 152

  Fly   171 VLPWTYCLVEWG-KSCV-------ATGATAANDSS-IVQGVSSAELFFTQTVLREPESLDDNGLG 226
            .|||..|..||. ::||       :...|:.|.:| :::       |:.:.||:..:.:..  ||
  Rat   153 DLPWGSCSHEWNTENCVEFQKTNNSLNVTSENATSPVIE-------FWERRVLKISDGIQH--LG 208

  Fly   227 TPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLK 291
            :..|:||||||..|:|....:.||::|:||..||.|.|||::::|||||.||||||.|||.::|.
  Rat   209 SLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLY 273

  Fly   292 PQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCII 356
            |..::|.:|.||..|.||:|||.|||.|.|....|:|.::.|.::|.:.:..::|.||.:||..|
  Rat   274 PNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTSFVAGFAI 338

  Fly   357 FGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMA 421
            |.|||.::.|... .||:|.:.|.|||||:||.|:....:.| |:|..||||:::||:.|.....
  Rat   339 FSILGFMSQEQGV-PISEVAESGPGLAFIAYPRAVVMLPFSP-LWACCFFFMVVLLGLDSQFVCV 401

  Fly   422 SAVVNVVKDRFTHL-----PHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LA 480
            .::|..:.|.:..:     ...:|.:..|::.|..||:.:|.||.:|..|.|:|..:.:.|: :|
  Rat   402 ESLVTALVDMYPRVFRKKNRREILILIVSVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVA 466

  Fly   481 IAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTY-RGVQ 544
            |.|.|.|.|:||..|...:||.|:..|.....:.||....|.:.....::.|..|.|||| :...
  Rat   467 IFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYT 531

  Fly   545 YPPVYYMAGWIIWGLGVLQLPFWAL 569
            ||......||::....::.:|.|::
  Rat   532 YPWWGDALGWLLALSSMVCIPAWSI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	183/495 (37%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:444915	196/536 (37%)