Protein Alignment CG8850 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_063131123.1
• Gene: Slc6a5 / 171148
• RGDID: 621824
• Length: 812
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 221/630 - (35%)
• Similarity: 344/630 - (54%)
• Gaps: 53/630 - (8%)

  Fly    29 DGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGG 93
            |||::|:..:.. ..||..:.:.:.:..|..||..::|:.|.:..:||||||||||::|.:||||
  Rat   179 DGIASVLPGSVA-TTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGG 242

  Fly    94 AFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQVYSTALATTYYACIMA 158
            ||||||:::|.|.|.|:::|||.:|||:|:|.:..:...|.::|.....:..:.|...||..|:.
  Rat   243 AFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIIC 307

  Fly   159 LTIRYLVASFSEVLPWTYCLVEWG------------KSCVA------------------TGATAA 193
            .|:.||.|||..||||..|...|.            .|||.                  ...|..
  Rat   308 YTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMV 372

  Fly   194 NDSSIVQG--VSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGK 256
            |.:|....  ||.:|.:|...||:....::..  |...|.|..||...|||:...|:|||::|||
  Rat   373 NFTSQANKTFVSGSEEYFKYFVLKISAGIEYP--GEIRWPLAFCLFLAWVIVYASLAKGIKTSGK 435

  Fly   257 ASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTL 321
            ..||.|.||||::::||||.||||||..||.||:.|:|.:|.:..||..|.||:||||:..:|.|
  Rat   436 VVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGL 500

  Fly   322 VMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFIS 386
            :..:|:|.|:.|.::|.:|:|..:|.|||.||.:||.::|.:|.|... :|..|...|.|:||:.
  Rat   501 ITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV-NIENVADQGPGIAFVV 564

  Fly   387 YPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRF-----THLPHWLLAVSASI 446
            ||||:.:....| .:|::||.|||.||:.:.......:|..:.|.|     ||.|  :..:...|
  Rat   565 YPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKP--VFTLGCCI 626

  Fly   447 IGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFY 511
            ..|:.|...:|.||.::..|||.|..::..:::||.||:.:.::||::|.|.|||.|:..:.:.:
  Rat   627 CFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIF 691

  Fly   512 WRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFWALVTIYQQP 576
            |::|||.|.|.::..:|.:..:.:||:||...:||....:.||::....|:.:|...::.:|..|
  Rat   692 WKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAP 756

  Fly   577 GKTFGSKFGLAMQPTANWGPLQTQKFEAYIIHR-KREADFKSPRG 620
            |: |..:..|...|..:|||...|       || :|..:...|.|
  Rat   757 GR-FIERLKLVCSPQPDWGPFLAQ-------HRGERYKNMIDPLG 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	189/510 (37%)
Slc6a5	XP_063131123.1	None