Protein Alignment CG8850 and Slc6a13

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_653095.1
• Gene: Slc6a13 / 14412
• MGIID: 95629
• Length: 602
• Species: Mus musculus
• Alignment Length: 549
• Identity: 205/549 - (37%)
• Similarity: 311/549 - (56%)
• Gaps: 23/549 - (4%)

  Fly    37 SAEGEELTINCEA----ESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLI 97
            ::.||...: |.|    |.:.:.:|:.|:..:||:.|.....:|||||||||::..:||||||.|
Mouse     9 TSNGETKPV-CPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFI 72

  Fly    98 PYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTI 161
            ||:|.|...|.||::||..:||::::|.|.|: .:.||..||.|......:|...||..::|..:
Mouse    73 PYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWAL 137

  Fly   162 RYLVASFSEVLPWTYCLVEWG-KSCVATGATAANDSSIV---QGVSSAELFFTQTVLREPESLDD 222
            .||.:||:..|||..|..||. ::||.  ...||||..|   ...|....|:.:.||:..:.:..
Mouse   138 FYLFSSFTTDLPWGSCSHEWNTENCVE--FQKANDSMNVTSENATSPVIEFWERRVLKLSDGIQH 200

  Fly   223 NGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIV 287
              ||:..|:||||||..|:|....:.||::|:||..||.|.|||::::|||||.||||||.|||.
Mouse   201 --LGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQ 263

  Fly   288 YFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILA 352
            ::|.|..::|.:|.||..|.||:|||.|||.|.|....|:|.::.|.::|.|.:..::|.||.:|
Mouse   264 FYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMA 328

  Fly   353 GCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSN 417
            |..||.|||.::.|... .||:|.:.|.|||||:||.|:....:.| |:|..||||:::||:.|.
Mouse   329 GFAIFSILGFMSQEQGV-PISEVAESGPGLAFIAYPRAVVMLPFSP-LWACCFFFMVVLLGLDSQ 391

  Fly   418 IGMASAVVNVVKDRFTHL-----PHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIAL 477
            .....::|..:.|.:..:     ...:|.:..|:|.|..||:.:|.||.:|..|.|:|..:.:.|
Mouse   392 FVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCL 456

  Fly   478 V-LAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTY- 540
            : :||.|.|.|.|:||..|...:||.|:..|.....:.||....|.:.....::.|..|.||||
Mouse   457 LFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYN 521

  Fly   541 RGVQYPPVYYMAGWIIWGLGVLQLPFWAL 569
            :...||......||::....::.:|.|::
Mouse   522 KKYTYPWWGDALGWLLALSSMICIPAWSI 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	187/484 (39%)
Slc6a13	NP_653095.1	SLC5-6-like_sbd	32..575	CDD:444915	200/525 (38%)