Protein Alignment CG8850 and DAT

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_061499264.1
• Gene: DAT / 1269812
• VectorBaseID: AGAMI1_006978
• Length: 678
• Species: Anopheles gambiae
• Alignment Length: 608
• Identity: 224/608 - (36%)
• Similarity: 333/608 - (54%)
• Gaps: 58/608 - (9%)

  Fly    10 LRRNMQGAQGSREGHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALS 74
            |.||  ||.|...|..|..|         :|||              |:.||..|:||.|.|..:
Mosquito    73 LPRN--GAGGGGGGGGGELD---------DGEE--------------RETWSGKVDFLLSVIGFA 112

  Fly    75 VGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFD-MAPIMRGI 138
            |.|.||||||::..:||||||||||.|:|::.|.|::|:|:.:|||:.:|.|..:. :.|:.:||
Mosquito   113 VDLANVWRFPYLCYKNGGGAFLIPYGIMLVVGGIPLFYMELALGQFNRKGAITCWGRLVPLFKGI 177

  Fly   139 AYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG----------KSCVA-----T 188
            .|..|........||..|:|.::|:..|||::.||||:|...|.          .|..|     |
Mosquito   178 GYAVVLIAFYVDFYYNVIIAWSLRFFFASFTDSLPWTHCSNAWNTVECKPFGYINSTAATVVNRT 242

  Fly   189 GATAANDSSIVQGV------SSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTIL 247
            |..|||.:..|..:      |:|..:|.:.:|...:|...:.||...||:.|||||.::|....|
Mosquito   243 GVLAANVTGTVSTINDTKFASAASEYFNRYILELDKSEGIHDLGAIKWDMALCLLAVYLICYFSL 307

  Fly   248 SKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFF 312
            .|||.:|||..:|.|||||.::::||:|.:||||:.:||:|:|:|.:..:.|..||..|.||:||
Mosquito   308 WKGISTSGKVVWFTALFPYAVLLILLVRGITLPGSAEGILYYLRPNFDVIYNAEVWVDAATQVFF 372

  Fly   313 SLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVK 377
            ||...||.|:.|||:|.::.||:||.::.:.|:|.||.:||.:||.:||.:| ..:.:.|..|..
Mosquito   373 SLGPGFGVLLAYASYNKYHNNVYKDALLTSLINSATSFIAGFVIFSVLGYMA-HASGQSIQDVAT 436

  Fly   378 GGAGLAFISYPEAIAKFKYLPQ--LFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHL---PH 437
            .|.||.|:.||.|||.   :|.  .:|::||.|||.||:.|:.|.:.|::..:.|.|..:   ..
Mosquito   437 EGPGLVFVVYPAAIAT---MPGSIFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIGRNRE 498

  Fly   438 WLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEF 502
            ..:||..|:. |:.||...|.||.:...|:|.|...:..|:....|.:||.||||.:|.|:||:.
Mosquito   499 IFVAVLFSLY-FVVGLASCTQGGFYFFQLLDRYAAGYSILIAVFFEAIAVSWIYGTERFCNDIKD 562

  Fly   503 MLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFW 567
            |:......|||:||..|||..:..:::|.|..:|||:|....||....:.||.|.|..::.:|..
Mosquito   563 MIGFAPGIYWRVCWKFVAPLFLLFIIIYGLIGHEPLSYEDYVYPSWANVLGWCIAGSSMIMIPLM 627

  Fly   568 ALVTIYQQPGKTFGSKFGLAMQP 590
            |...:...|| :...:|.:...|
Mosquito   628 ASYKLIVTPG-SLRQRFKILTTP 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	194/500 (39%)
DAT	XP_061499264.1	None