Protein Alignment CG8850 and Slc6a20a

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_631881.1
• Gene: Slc6a20a / 102680
• MGIID: 2143217
• Length: 592
• Species: Mus musculus
• Alignment Length: 573
• Identity: 184/573 - (32%)
• Similarity: 293/573 - (51%)
• Gaps: 100/573 - (17%)

  Fly    57 RDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFS 121
            |.||...::|:|:||:.:||||||||||::....|||:||:||:|:|::.|.|:.|||:.:||..
Mouse     5 RPQWGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRM 69

  Fly   122 SRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVE----- 180
            .:|.|.|: .::|.:.|:....|..:...:.||..|.|....||..||.:.|||:.|.:.
Mouse    70 RQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNHTG 134

  Fly   181 WGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGT 245
            :.:.|              :..||.:.|:.:..|....|:.:|| |. .|:..|||...|:::..
Mouse   135 YDEEC--------------EKASSTQYFWYRKTLNISPSIQENG-GV-QWEPALCLTLAWLMVYL 183

  Fly   246 ILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQM 310
            .:.:|..|:||..||.|..||.::|:.|:|.:||.||..|::|...|:..||.||..|..|.||:
Mouse   184 CILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQI 248

  Fly   311 FFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLA---FE------ 366
            ||||.:.||:|:.:||:|:.:.|..|..||::.|:|.|||.|..:.|.|.|..|   :|
Mouse   249 FFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKV 313

  Fly   367 ----TNTKDIS---------QVVKG-------------------------------GAGLAFISY 387
                ||:.|:.         :.||.                               |.|||||.|
Mouse   314 ILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVY 378

  Fly   388 PEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDR---FTHLPHWLLAVSASIIGF 449
            .|||...: :.||::||:|||||:|||||.:|..:|::..:.|.   .::||...::....:|..
Mouse   379 TEAIKNME-VSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINC 442

  Fly   450 LCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRI 514
            ..|:|:....|.:..::.:.|..|...|::.:.|.:||.::||:||..||:..|.....|:||::
Mouse   443 AVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKV 507

  Fly   515 CWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFW 567
            .||.|:|     :|:..||              ::|::.:|:  .|.||...|
Mouse   508 MWAFVSP-----LLIVGLF--------------IFYLSDYIL--TGTLQYQAW 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	175/535 (33%)
Slc6a20a	NP_631881.1	SLC5-6-like_sbd	2..577	CDD:294310	184/573 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810