Protein Alignment CG8850 and slc6a16

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_004916326.1
• Gene: slc6a16 / 100497867
• XenbaseID: XB-GENE-996340
• Length: 677
• Species: Xenopus tropicalis
• Alignment Length: 683
• Identity: 190/683 - (27%)
• Similarity: 301/683 - (44%)
• Gaps: 155/683 - (22%)

  Fly    37 SAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVI 101
            |..||.......|||.:   |..|...|:::.:.:..|||||||||||::..:||||:||:.|.:
 Frog    11 STAGESQLGLLPAESVA---RPTWGSKVQYILAQVGFSVGLGNVWRFPYLCHQNGGGSFLLLYFL 72

  Fly   102 VLLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLV 165
            :||:||.|:::||:..||...:|.|..: .::|.:.||.:...........||..|:..::.||.
 Frog    73 LLLIIGIPLFFLELAAGQSIRQGSIGVWKHISPRLAGIGFASCVVCGFVALYYNVIIGWSLFYLF 137

  Fly   166 ASFSEVLPWTYC---------LVEWGKSCVATGATAANDSSIVQGVSSAELFFTQTVLREPESLD 221
            .||...|||..|         :.|..||                  |:...|:.::.|....:::
 Frog   138 NSFHYPLPWENCPTLPNMTQEVTECAKS------------------SNTTYFWYRSALNVTNTIE 184

  Fly   222 DNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGI 286
            .:.:   :|.:..||...|.::...:.|||:||||..||.::||||::...|||.:.|.||..||
 Frog   185 SSEM---NWPMTGCLCLAWFLVCGGMIKGIKSSGKVMYFSSVFPYVVLFCFLIRGLLLEGAADGI 246

  Fly   287 VYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSIL 351
            .....|:.....|..||..|.||:||:|.:.||:::.|:|:||...|.|.|.|:::.|:.:||||
 Frog   247 RIMFTPKLEIWGNIQVWRQAATQVFFALGLGFGSVIAYSSYNDRQNNCHFDAILVSFINFMTSIL 311

  Fly   352 AGCIIFGILGNLA-------FETNTKDISQVVKGGA----------------------------- 380
            |..::|.:||..|       .:||.:.|..::..|:
 Frog   312 ATLVVFAVLGFRANDLTRHCIDTNREKILYLISNGSLYENIVPMKNLTNSEYSQWYEITNNTLNL 376

  Fly   381 ---------------------GLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAV 424
                                 |||||::.||:.:|...| .:::|||.|||.||:.:..|....:
 Frog   377 QQYGISDCRVEDVMNEGVEGTGLAFIAFTEAMTRFPASP-FWSILFFLMLLNLGLSTMFGNMQGI 440

  Fly   425 VNVVKDRFTHL--PHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAV 487
            :..:.|.|.:|  ...:..|...|.|.|.||:::...|.:.:::.|.|..|...:::.|.|.:||
 Frog   441 ITPLLDNFPYLRKKKTIFTVICCITGLLIGLIFVQRSGSYFVSMFDDYSATLPLIIVVIFENIAV 505

  Fly   488 GWIYGVKRICSDIEFMLNVKTSFYWRI---CWAIVA----PGLMFLVLVYMLFSY--------EP 537
            .|:||.:|...||..||..:.   |||   .|..::    .||:...|:.|...|        |.
 Frog   506 AWVYGAERFMDDIGGMLGHRP---WRIYKYIWQYISILGMIGLLLASLIRMCIEYPRYQAWNQEQ 567

  Fly   538 LTYRGVQYPPVYYMAGWIIWGLGVL-------QLPF---------------WALVTI----YQQP 576
            .....::|||         |.||:|       .||.               |...|.    |.|
 Frog   568 AKKEMLEYPP---------WALGMLTSLIIVAALPIPIVFLKHIIQDWILKWKTKTYGDCDYTQ- 622

  Fly   577 GKTFGSKFGLAMQPTANWG-------PLQTQKF 602
            |.|.....|..::..|:.|       |::.:.|
 Frog   623 GNTVDDMIGPIVESPADLGYVGNGYLPVEMEDF 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	160/549 (29%)
slc6a16	XP_004916326.1	SLC5-6-like_sbd	28..599	CDD:444915	173/604 (29%)