Protein Alignment CG8850 and slc6a5

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_031756248.1
• Gene: slc6a5 / 100495275
• XenbaseID: XB-GENE-993852
• Length: 789
• Species: Xenopus tropicalis
• Alignment Length: 644
• Identity: 229/644 - (35%)
• Similarity: 349/644 - (54%)
• Gaps: 57/644 - (8%)

  Fly    14 MQGAQGSREGHPGSND------------GISTVIYSAEGEEL----TINCEAESESSGQRDQWSR 62
            :|.|:|......|.|.            ..|||:...:|...    |:|.:.|.:.:..|..||.
 Frog   124 LQSAEGETNQGFGKNSLEQNNAKGGWVPSQSTVVLGTDGNTSVFPGTLNGDEEGDENKARGNWSS 188

  Fly    63 GVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIR 127
            .::|:.|.:..:||||||||||::|.:||||||||||:.:|.|.|.|::|:||.:|||:|:|.|.
 Frog   189 KLDFILSMVGYAVGLGNVWRFPYLAFKNGGGAFLIPYLTMLALAGLPIFYMEVALGQFASQGPIS 253

  Fly   128 AFDMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG---------- 182
            .:...|.::|.....:..:.|...||..||..||.||.||...||||..|...|.
 Frog   254 VWKAIPALQGCGIAMLIISVLIAIYYNIIMCYTIFYLFASLVSVLPWASCTNPWNTPDCKDKDRL 318

  Fly   183 --KSCVATG------------ATAANDSSIV--------QGVSSAELFFTQTVLREPESLDDNGL 225
              .||:...            .||..:.::|        ..||.:|.:|...:|:....::..
 Frog   319 MLDSCIIGSQPNIHIKNSTFCMTAYPNLTLVNFTSHANKSFVSGSEEYFKYNMLKISAGIEYP-- 381

  Fly   226 GTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFL 290
            |...|.|.:||...|.|:...|:|||:||||..||.|.||||::::||||.||||||..||.:|:
 Frog   382 GEIRWPLAICLFLAWTIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGDGIWWFI 446

  Fly   291 KPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCI 355
            .|:|.:|::..||..|.||:||||:..:|.|:..:|:|.|:.||::|.:|:|..:|.|||.||.:
 Frog   447 MPKWEKLMDAMVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNVYRDTLIVTCTNSATSIFAGFV 511

  Fly   356 IFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGM 420
            ||.::|.:|...|. ||.:|...|.|:||:.||||:.:....| .:|::||.|||.||:.:....
 Frog   512 IFSVIGFMAHILNV-DIEKVADQGPGIAFVVYPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFAT 574

  Fly   421 ASAVVNVVKDRFTHL--PHW-LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIA 482
            ...:|..|.|.|..|  ||. |..:...:..|:.|...:|.||.::|.|||.|..::..:::||.
 Frog   575 IETIVTSVSDEFPKLLRPHKPLFTLICCVAFFIMGFPMITQGGIYMLQLVDNYAASYSLVIIAIF 639

  Fly   483 ELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPP 547
            ||:.:.::||::|.|.|||.|:..:.|.:|::|||.|.|.::..:|.:..:.:||:||....||.
 Frog   640 ELVGISYVYGLQRFCEDIEMMIGFQPSRFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYHYPT 704

  Fly   548 VYYMAGWIIWGLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQPTANWGP-LQTQKFEAY 605
            ...:.||::....|:.:|...::.:|..|| ||..:..|...|..:||| |...:.|.|
 Frog   705 WSMVMGWLMLACSVIWIPVMFVIKMYLAPG-TFIERLKLVCSPQPDWGPFLAKHRGERY 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	193/508 (38%)
slc6a5	XP_031756248.1	SLC6sbd_GlyT2	183..779	CDD:271389	217/585 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110