Protein Alignment CG8850 and slc6a6

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 203/551 - (36%)
• Similarity: 308/551 - (55%)
• Gaps: 34/551 - (6%)

  Fly    50 ESESSG---QRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVY 111
            |.|:.|   ||::|:..::|:.|.....:|||||||||::..:||||||||||.|.|...|.||:
 Frog    31 EDEADGKPPQREKWASKIDFVLSVAGGFIGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVF 95

  Fly   112 YLEVIIGQFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWT 175
            :|||::|||:|.|.|..:: :.|:..||.|..:...:|...||..|:|..:.||..||...|||.
 Frog    96 FLEVVLGQFTSEGGITCWEKICPVFTGIGYASIVIVSLLNVYYIVILAWGVYYLFQSFQGQLPWA 160

  Fly   176 YCLVEWG-KSCVA-------TGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDL 232
            .|...|. :|||.       |...:.|.::....|:.   |:...||...:.:||  :|...|||
 Frog   161 LCHQPWNTESCVEDTFRKNWTMWMSMNSTNFTSPVTE---FWEHKVLSLSKGIDD--VGVLKWDL 220

  Fly   233 VLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQL 297
            .||||.||||....:.||:||:||..||.|.||:::::|||||.||||||.:||.::|.|..::|
 Frog   221 ALCLLLTWVICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRGVTLPGAAEGIKFYLYPDITRL 285

  Fly   298 LNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGN 362
            .:|.||..|.||:|||.|||.|.:....|:|.:..|.::|.:::..::|.||.::|..||.:||.
 Frog   286 ADPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGF 350

  Fly   363 LAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNV 427
            :|.|... ||:.|.:.|.|||||:||:|::... ||..:|:|||.|||:||:.|........:..
 Frog   351 MAQEQGV-DIADVAESGPGLAFIAYPKAVSMMP-LPSFWAILFFIMLLLLGLDSQFVEVEGQITS 413

  Fly   428 VKDRFTHLPHWL---------LAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIA 482
            :.|.:   |.:|         :|| ...:.:|.||..:|.||.:|..|.|:|..:.:.|: :|..
 Frog   414 LVDLY---PSFLRKGYRREIFIAV-VCFLSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFF 474

  Fly   483 ELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTY-RGVQYP 546
            |.:||.|:||..:...:||.|:..|...:.:..|.::.|.|.....::.|..|.|||| :...||
 Frog   475 ECVAVAWVYGADKFYDNIEDMIGYKPGPWMKWSWTVITPLLCVACFIFSLAKYTPLTYNKYYVYP 539

  Fly   547 PVYYMAGWIIWGLGVLQLPFWALVTIYQQPG 577
            ......||::....::.:|...:..|.:..|
 Frog   540 DWAIGLGWVLALSSMICIPLVVVFHIVRSDG 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	185/492 (38%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	199/541 (37%)