Protein Alignment CG8850 and slc6a4

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_017946918.1
• Gene: slc6a4 / 100493853
• XenbaseID: XB-GENE-22062972
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 215/603 - (35%)
• Similarity: 325/603 - (53%)
• Gaps: 66/603 - (10%)

  Fly    19 GSREGHPGSNDGISTVIYSAE---------GEE-----LTI--NCEAESE----SSGQRDQWSRG 63
            |.| |.||........:.|.|         |:|     ||:  .|.||.:    ..|:|:.||:.
 Frog    56 GER-GEPGHISNKYLAVQSPEAPCNGMRNGGDEGSTPTLTVLPACRAEIQHLQTEIGERETWSKK 119

  Fly    64 VEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRA 128
            ::||.|.|..:|.||||||||::..:||||||||||||:.:..|.|::|:|:.:||:...|||..
 Frog   120 IDFLLSVIGYAVDLGNVWRFPYVCYQNGGGAFLIPYVIMAVFGGIPLFYMELAMGQYHRNGCISI 184

  Fly   129 F-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGK-SCV---AT 188
            : .:.|:.:||.|...........||..|||..:.||:.||...||||.||.||.. :|.   ..
 Frog   185 WRKICPLFKGIGYAICMIALYVAFYYNTIMAWALYYLIFSFRSELPWTSCLNEWNTGNCTNYFQN 249

  Fly   189 GATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRS 253
            .:...::|||    |.||.|:|:.||:..:|...:.||..||.|.||||..:.::...:.||:::
 Frog   250 SSVGWSNSSI----SPAEEFYTRLVLQIHKSKGLHDLGGISWQLTLCLLLIFTVVYFSIWKGVKT 310

  Fly   254 SGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICF 318
            |||..:..|.|||:::.:||||..||||||:|::::|:|.|.:||...||..|..|:||||...|
 Frog   311 SGKVVWVTATFPYIVLALLLIRGATLPGAWRGVLFYLQPDWEKLLTTAVWVDAAAQIFFSLGPGF 375

  Fly   319 GTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKG-GAGL 382
            |.|:.:||:|.|:.|.::|.:|.:|::.:||.::|.:||.:||.:| |....|:|:|.|. |..|
 Frog   376 GVLLAFASYNKFHNNCYQDALITSTVNCMTSFMSGLVIFTVLGYMA-EMRNLDVSEVAKDTGPSL 439

  Fly   383 AFISYPEAIAKFKYLP--QLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHW------- 438
            .||:|.||||.   :|  ..||::||.||:.||:.|.......|:..|.|.|.|:  |
 Frog   440 LFITYAEAIAN---MPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHI--WGKRRELF 499

  Fly   439 -LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEF 502
             .|.:|...:|.|..|.:   ||.:::.|.:.|......|.:...|.:||.|.||:.:.|.|:..
 Frog   500 VFLLISVCFLGALSTLTF---GGAYMVKLFEEYATGPAVLTVVFLEAIAVSWFYGINQFCRDVRE 561

  Fly   503 MLNVKTSFYWRICWAIVAP-GLMFLVLVYM-------LFSYEPLTYRGVQYPPVYYMAGWIIWGL 559
            ||.....::|:|||..:.| .|:|::..:|       ||:|        |||....:.|:.|...
 Frog   562 MLGFSPGWFWKICWVAICPLFLLFIICSFMSSPPDLRLFNY--------QYPSWTVVLGYCIGTS 618

  Fly   560 GVLQLPFWALVTIYQQPG 577
            ..:.:|.:.:..:...||
 Frog   619 SFICVPAYMVYLLTSTPG 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	188/497 (38%)
slc6a4	XP_017946918.1	5HT_transport_N	48..91	CDD:367522	9/35 (26%)
		SLC5-6-like_sbd	113..649	CDD:382020	200/545 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010