DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8850 and LOC100490052

DIOPT Version :9

Sequence 1:	NP_725122.2	Gene:	CG8850 / 36331	FlyBaseID:	FBgn0033708	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_002942758.1	Gene:	LOC100490052 / 100490052	-ID:	-	Length:	649	Species:	Xenopus tropicalis

Alignment Length:	643	Identity:	222/643 - (34%)
Similarity:	323/643 - (50%)	Gaps:	79/643 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QGA--QGSREGHPGSNDGISTVIYSAEGEELTINCE-AESESSG-QRDQWSRGVEFLFSCIALSV 75
            :||  .|..:..|||..|.     |.:|.:.....| |....:| .|:.|....|||.|||...|
Frog    29 EGAASPGRAQDPPGSEPGT-----SQDGTDAQRVAELAPPAPAGPPRETWGGKYEFLLSCIGYCV 88

  Fly    76 GLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAY 140
            |||||||||::...||||||||||.|:|...|.|::.:|:.:||:.:.|.|..:...||::||..
Frog    89 GLGNVWRFPYLCYRNGGGAFLIPYSIMLFFTGLPLFLMELSLGQYGAAGPITVWKCCPILKGIGI 153

  Fly   141 GQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGKSCVATGATAANDSSIVQGVSSA 205
            |.:..:||.:.||..|:|.|..||..||...|||:.....:.:.|       .|.:|.....|:.
Frog   154 GMLLVSALVSLYYNVIIAWTFYYLGQSFQSPLPWSCDSALYSQLC-------QNGTSNGSQFSAT 211

  Fly   206 ELFFTQTVLREPESLDDNGLGTP---SWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYV 267
            |.|:.:.||....|   :|||.|   .|:|.|||||.|.||...:.|||.||||..||.|.|||.
Frog   212 EAFWNEKVLGVTHS---SGLGDPGPVGWELALCLLAAWFIIFLCMLKGIHSSGKIVYFTATFPYF 273

  Fly   268 IMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNK 332
            :|:||:||..||.|:..|:.::|...|.:|.:..||..|.:|:|:||.|.||.|:..||:|.||.
Frog   274 VMVVLIIRGATLEGSIDGVRFYLTADWKRLQSAQVWNDAASQIFYSLGIGFGGLLSMASYNKFNN 338

  Fly   333 NVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKFKYL 397
            ||.:|.::|...:..||..||..||.:||::|::... .:.||...|.||||::||||:|   .|
Frog   339 NVIRDTLVIAIGNCSTSFFAGFAIFSVLGHMAWKKGV-PVGQVADSGPGLAFVAYPEALA---LL 399

  Fly   398 P--QLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLLAVSASIIGFLC------GLV 454
            |  ..:::|||.||..||:.:..|....:...:.|....|..|  ......:|.||      ||:
Frog   400 PGSVFWSILFFLMLFTLGVDTLFGNMEGITTAILDEIPSLRDW--KRKTIFLGCLCFAFYLLGLL 462

  Fly   455 YMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLN------VKTSFYWR 513
            .:|.||.:...|:|.|..:|..:::|:...|.:.:.|||.:.|.||..|::      .|..:|::
Frog   463 LITQGGIYWFTLIDSYSTSFGLIIIALFMCLGIAFFYGVNQFCQDILDMVSQCPPWCTKVLWYFK 527

  Fly   514 ICWAIVAPGLMFLVLVYMLFSY--EPLTYRGVQYPPVYYMAGWIIWG--LGV-------LQLPFW 567
            .||..:.|.|:..:|.|:....  .||.|....||.         ||  ||:       :|:|.|
Frog   528 ACWVFITPLLLLFILFYIFLEMYNTPLRYGAYVYPR---------WGQALGICMGTLCCIQIPIW 583

  Fly   568 ALVTIYQQPGKTFGSKFGLAMQPTANWGPLQTQKFEAYIIHRKREADFKSPRGGYLFD 625
            |.|.:.::.| |...:|..:::|...|                |.|:.....|..:.|
Frog   584 ATVAVLKETG-TLKERFKKSLRPLNTW----------------RNANSPQEHGNAIID 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	186/490 (38%)
LOC100490052	XP_002942758.1	SLC5-6-like_sbd	70..610	CDD:382020	206/581 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010