DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and MYL10

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_612412.2	Gene:	MYL10 / 93408	HGNCID:	29825	Length:	226	Species:	Homo sapiens

Alignment Length:	182	Identity:	54/182 - (29%)
Similarity:	81/182 - (44%)	Gaps:	42/182 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADQLTEEQIAEFKE----------------------------------AFSLFDKDGDGTITTK 31
            |.||   .||.||||                                  ||::.|::.||.|..:
Human    46 MFDQ---SQIQEFKESLALSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKE 107

  Fly    32 ELGTVMRSLGQ-NPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDK 95
            :|.....:||: |....||:.|:.|..    |.|:|..||||...|:|.||.||.|..||:|||.
Human   108 DLRDTFAALGRINVKNEELEAMVKEAP----GPINFTVFLTMFGEKLKGTDPEETILHAFKVFDT 168

  Fly    96 DGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147
            :|.||:.|..::..:....::.::|||.:|......|..|.::|.....::|
Human   169 EGKGFVKADVIKEKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVIT 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	54/182 (30%)
MYL10	NP_612412.2	FRQ1	40..223	CDD:227455	54/182 (30%)
		EF-hand motif	89..118	CDD:320054	8/28 (29%)
		EF-hand motif	149..187	CDD:320054	16/37 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910