DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and EFHD2

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_077305.2	Gene:	EFHD2 / 79180	HGNCID:	28670	Length:	240	Species:	Homo sapiens

Alignment Length:	137	Identity:	36/137 - (26%)
Similarity:	62/137 - (45%)	Gaps:	11/137 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 68
            :.:.:||.:.::.|..:|...||.|...||..:|..||...|...|::||.|||.|.:..:.|.|
Human    88 EFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFRE 152

  Fly    69 FLTMMARKMKDTDSEEE----IREAFRVFDKDGNGFISAA---ELRHVMTNLGEKLTDE---EVD 123
            || ::.||....:.:|:    :.......|....|...|.   |.:....|:..:..:|   |.:
Human   153 FL-LIFRKAAAGELQEDSGLCVLARLSEIDVSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQE 216

  Fly   124 EMIREAD 130
            |..::|:
Human   217 ERKKQAE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	36/137 (26%)
EFHD2	NP_077305.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..38
EFHD2	NP_077305.2	EFh	96..154	CDD:238008	20/57 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910