DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and MYL3

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_000249.1	Gene:	MYL3 / 4634	HGNCID:	7584	Length:	195	Species:	Homo sapiens

Alignment Length:	151	Identity:	67/151 - (44%)
Similarity:	97/151 - (64%)	Gaps:	7/151 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QLTEEQIAEFKEAFSLFDKDG--DGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT--I 64
            :.|.|||.||||||.|||:..  :..||..:.|.|:|:||||||:||:..::.:...:...|  :
Human    45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109

  Fly    65 DFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIR 127
            ||..||.|:..  |.|||.:.|:..|..|||||:|||.:..||||||:..|||:||::||::::.
Human   110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMA 174

  Fly   128 EADIDGDGQVNYEEFVTMMTS 148
            ..: |.:|.:|||.||..:.|
Human   175 GQE-DSNGCINYEAFVKHIMS 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	67/151 (44%)
MYL3	NP_000249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
MYL3	NP_000249.1	PTZ00184	44..194	CDD:185504	66/149 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910