DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cam and rcn3

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_001002158.1	Gene:	rcn3 / 415248	ZFINID:	ZDB-GENE-040625-175	Length:	316	Species:	Danio rerio

Alignment Length:	145	Identity:	41/145 - (28%)
Similarity:	68/145 - (46%)	Gaps:	27/145 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE------LQDMINEVDADGNGTIDFPEFLT 71
            ||.|    |:||||..|.:|....:     :|.|.:      :|:.|.::|.:|:|.||..|::.
Zfish   160 FKSA----DRDGDGVATREEFTAFL-----HPEEFDFMRDIVIQETIEDIDKNGDGKIDLQEYIG 215

  Fly    72 MMARKMKDTDSE--------EEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIRE 128
            .|... :|.::|        ::..| ||..:||  ||:.|.|:.|.:........|.|...:|.|
Zfish   216 DMYNP-EDGETEPDWVTTEKKQFSE-FRDMNKD--GFLDATEVSHWILPTEVDHADNEARHLIHE 276

  Fly   129 ADIDGDGQVNYEEFV 143
            .|.|.|.::..:|.:
Zfish   277 TDKDNDDKITKKEIL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	41/145 (28%)
rcn3	NP_001002158.1	EF-hand_7	71..128	CDD:290234
		EFh	73..122	CDD:298682
		EF-hand_7	157..214	CDD:290234	20/62 (32%)
		EFh	157..214	CDD:238008	20/62 (32%)
		EFh	193..258	CDD:298682	21/68 (31%)
		EFh	234..292	CDD:298682	18/61 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910