DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and efcab7

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_001002120.1	Gene:	efcab7 / 415210	ZFINID:	ZDB-GENE-040625-115	Length:	603	Species:	Danio rerio

Alignment Length:	122	Identity:	40/122 - (32%)
Similarity:	78/122 - (63%)	Gaps:	7/122 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ITTK-ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR 91
            :|:| :|.||::..|:||:    |..:::....|...::|.:|..:: :|.|.|: .:::...|:
Zfish    28 MTSKDQLCTVLQQAGRNPS----QKALDKYWPPGTKKLNFDDFCEIL-KKEKKTE-PDQLMTIFK 86

  Fly    92 VFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTS 148
            .||.:|:|:||..||..::|:.|||::.:||||:...||::.||:::|.||..::.|
Zfish    87 KFDTNGDGYISHDELSRILTSSGEKMSHKEVDEIFTLADVNKDGKLDYAEFCRLLGS 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	40/122 (33%)
efcab7	NP_001002120.1	EF-hand_8	57..100	CDD:290545	13/44 (30%)
		EFh	80..141	CDD:238008	24/60 (40%)
		EF-hand_7	81..141	CDD:290234	24/59 (41%)
		EFh	380..439	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910