DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and calb2b

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_957005.1	Gene:	calb2b / 393684	ZFINID:	ZDB-GENE-040426-1668	Length:	269	Species:	Danio rerio

Alignment Length:	166	Identity:	41/166 - (24%)
Similarity:	79/166 - (47%)	Gaps:	24/166 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL-----GQNPTEAELQDMINE----VDADG 60
            |.|...::|.:.::.||.||:|.|..|||...:|.|     ..:|:.|..:|.:.|    .|.:|
Zfish    13 LAELTASQFLDIWNKFDADGNGCIEGKELENFIRELEIARKTADPSNASFKDRMKEFMQKFDENG 77

  Fly    61 NGTIDFPEFLTMMARK-------MKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNL----- 113
            :|.|:..|...::..:       .:...|..|...|:|.:|.|.:|:|.:.||:..:::|
Zfish    78 DGKIEMSELAQILPTEENFLLCFRQFVGSSAEFMTAWRKYDTDRSGYIESNELKGFLSDLLKKAN 142

  Fly   114 ---GEKLTDEEVDEMIREADIDGDGQVNYEEFVTMM 146
               .:|..:|....:::..|::|||::...|...::
Zfish   143 RHYNDKKLNEYTQTILKMFDLNGDGKLGLSEMARLL 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	41/166 (25%)
calb2b	NP_957005.1	PTZ00184	13..178	CDD:185504	41/164 (25%)
		EFh	20..90	CDD:238008	21/69 (30%)
		EFh	109..178	CDD:238008	17/68 (25%)
		EF-hand_7	155..218	CDD:290234	5/24 (21%)
		EFh	157..223	CDD:238008	5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910