DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and mlc-3

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_741145.1	Gene:	mlc-3 / 175768	WormBaseID:	WBGene00003371	Length:	153	Species:	Caenorhabditis elegans

Alignment Length:	133	Identity:	50/133 - (37%)
Similarity:	79/133 - (59%)	Gaps:	4/133 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI-NEVDADGNGTIDFPEFLTMMAR-- 75
            ||.|:|:|::.||.|...::|.|.|:.|..||:|.:.... .|....|...:.|.|:|.|..:
Worm    10 KEIFNLYDEELDGKIDGTQVGDVARAAGLKPTQAMVTKAAGQEFKRKGEKRLTFEEWLPMYEQLA 74

  Fly    76 KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140
            |.|:..:..:..|..:||||:..|.|.||||||::..|||:|:.:|.||:::..: ||:|.|.||
Worm    75 KEKEQGTYADFYEGLKVFDKEETGKILAAELRHILLALGERLSADEADELLKGVE-DGEGMVKYE 138

  Fly   141 EFV 143
            :|:
Worm   139 DFI 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	50/133 (38%)
mlc-3	NP_741145.1	EF-hand_7	9..70	CDD:290234	20/59 (34%)
mlc-3	NP_741145.1	EFh	90..142	CDD:298682	26/53 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910