DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and H10E21.4

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_497128.1	Gene:	H10E21.4 / 175168	WormBaseID:	WBGene00019184	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	137	Identity:	40/137 - (29%)
Similarity:	70/137 - (51%)	Gaps:	16/137 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM---MARK 76
            ::|.|.|.:.||.::.|||.|.||..|:    .:.|:.....|.|.||.:|..||:.:   |:|:
Worm    21 DSFDLVDANNDGKLSEKELITFMRKRGR----PDGQEYFQRFDLDRNGHLDISEFVPLVYEMSRR 81

  Fly    77 MKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEE 141
            ..|.|     .|.|:..|.:.:|.:..||:..:..:..:::    :|.::..||.:.|||:.|.|
Worm    82 PVDMD-----YEFFKKMDLNDDGIVDKAEVEKIRKDNNDRI----IDGILSIADTNRDGQLTYAE 137

  Fly   142 FVTMMTS 148
            |...::|
Worm   138 FKNHLSS 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	40/137 (29%)
H10E21.4	NP_497128.1	EF-hand_7	21..75	CDD:290234	20/57 (35%)
		EFh	23..72	CDD:238008	19/52 (37%)
		EF-hand_7	87..139	CDD:290234	14/55 (25%)
		EFh	88..143	CDD:298682	15/58 (26%)
		EF-hand_7	161..219	CDD:290234
		EFh	166..221	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910