DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and CALML6

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	XP_005244786.2	Gene:	CALML6 / 163688	HGNCID:	24193	Length:	203	Species:	Homo sapiens

Alignment Length:	150	Identity:	67/150 - (44%)
Similarity:	97/150 - (64%)	Gaps:	1/150 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 65
            |.::|:.|||.|:|..|.:||::|:|.:.|.||..:|..||.|||::||..|..:||.|..|..:
Human    48 MTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRDNKGFFN 112

  Fly    66 FPEFLTMM-ARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREA 129
            ...||.:| ....|..:.|.|:|.|||||||:|.|:|....|::|:.|.||.|.:.|.::|::||
Human   113 CDGFLALMGVYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEA 177

  Fly   130 DIDGDGQVNYEEFVTMMTSK 149
            |.|||..::|||||.|||.:
Human   178 DKDGDRTIDYEEFVAMMTGE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	67/148 (45%)
CALML6	XP_005244786.2	PTZ00184	48..195	CDD:185504	65/146 (45%)
		EFh	59..120	CDD:238008	25/60 (42%)
		EFh	133..195	CDD:238008	32/61 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010