DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and Ncs1

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_062655.1	Gene:	Ncs1 / 14299	MGIID:	109166	Length:	190	Species:	Mus musculus

Alignment Length:	144	Identity:	34/144 - (23%)
Similarity:	67/144 - (46%)	Gaps:	32/144 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 75
            |.|::.:..|...||.|    :..|.               :.|..|.:.:|.|:|.||:..::.
Mouse    46 AGFQKIYKQFFPFGDPT----KFATF---------------VFNVFDENKDGRIEFSEFIQALSV 91

  Fly    76 KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGE------KLTDEE------VDEMIRE 128
            ..:.| .:|::|.||:::|.|.:|:|:..|:..::..:.:      :|.:||      ||.:...
Mouse    92 TSRGT-LDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAM 155

  Fly   129 ADIDGDGQVNYEEF 142
            .|.:.||::..:||
Mouse   156 MDKNADGKLTLQEF 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	34/144 (24%)
Ncs1	NP_062655.1	FRQ1	20..179	CDD:227455	34/144 (24%)
Ncs1	NP_062655.1	Interaction with IL1RAPL1. /evidence=ECO:0000250\|UniProtKB:P62166	174..190
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53747
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010