DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cam and Calu

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_031620.1	Gene:	Calu / 12321	MGIID:	1097158	Length:	315	Species:	Mus musculus

Alignment Length:	147	Identity:	38/147 - (25%)
Similarity:	68/147 - (46%)	Gaps:	15/147 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAE------LQDMINEVDADGNGTID 65
            ::.:...:..|.:.||||| .|.|||..|..    .:|.|.:      :|:.:.::|.:.:|.||
Mouse   150 KQMMVRDERRFKMADKDGD-LIATKEEFTAF----LHPEEYDYMKDIVVQETMEDIDKNADGFID 209

  Fly    66 FPEFLTMMARKMKDTDSEEEI---REAFRVF-DKDGNGFISAAELRHVMTNLGEKLTDEEVDEMI 126
            ..|::..|.....:.|..|.:   ||.|..| ||:.:|.:...|.:..:........:.|...::
Mouse   210 LEEYIGDMYSHDGNADEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLV 274

  Fly   127 READIDGDGQVNYEEFV 143
            .|:|.:.||::..||.|
Mouse   275 YESDQNKDGKLTKEEIV 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	38/147 (26%)
Calu	NP_031620.1	EFh_CREC_Calumenin	37..299	CDD:320026	38/147 (26%)
		EF-hand motif	37..66	CDD:320026
		EF-hand motif	72..101	CDD:320026
		EF-hand motif	108..137	CDD:320026
		EF-hand motif	155..184	CDD:320026	12/33 (36%)
		EF-hand motif	192..221	CDD:320026	7/28 (25%)
		EF-hand motif	233..262	CDD:320026	8/28 (29%)
		EF-hand motif	269..299	CDD:320026	8/23 (35%)
		Prevents secretion from ER	312..315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910