DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cam and CIB2

DIOPT Version :9

Sequence 1:NP_001246276.1 Gene:Cam / 36329 FlyBaseID:FBgn0000253 Length:149 Species:Drosophila melanogaster
Sequence 2:XP_005254183.1 Gene:CIB2 / 10518 HGNCID:24579 Length:210 Species:Homo sapiens


Alignment Length:115 Identity:33/115 - (28%)
Similarity:59/115 - (51%) Gaps:8/115 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 MRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFI 101
            |..|.:||.:..:....:|   ||.|.:.|.:|:.|.:...:....|.:...||:::|.:.:.||
Human    62 MPELRENPFKERIVAAFSE---DGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFI 123

  Fly   102 SAAELRHVMTNLGEKLTDEE-----VDEMIREADIDGDGQVNYEEFVTMM 146
            ...:|...:..|.:...|||     .|::|.|||:||||::.:.:|..|:
Human   124 CKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMI 173

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CamNP_001246276.1 PTZ00184 1..149 CDD:185504 33/115 (29%)
CIB2XP_005254183.1 EFh 107..174 CDD:238008 21/67 (31%)
EF-hand_7 111..173 CDD:290234 20/61 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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