DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cam and duox2

DIOPT Version :9

Sequence 1:	NP_001246276.1	Gene:	Cam / 36329	FlyBaseID:	FBgn0000253	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	XP_017947900.2	Gene:	duox2 / 100486050	XenbaseID:	XB-GENE-6047411	Length:	1517	Species:	Xenopus tropicalis

Alignment Length:	167	Identity:	41/167 - (24%)
Similarity:	77/167 - (46%)	Gaps:	26/167 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADQLTEEQIAEFKEAF---SL-----FDKDGDGTITTKELGTVMR----------SLGQNPTEA 47
            :.:..|::|..:..|.|   ||     .:|:..||...:....|::          |||.||...
Frog   743 LKESFTKKQRQQMLETFIRHSLSHVIDINKEHAGTTQGQNFRDVLQCELSREEFADSLGLNPNAQ 807

  Fly    48 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAE------- 105
            .::.|.:..|.|.||.:.|.||..::...:|.: :|::::..|.:.|.:|||.:...|
Frog   808 FVESMFSMADKDHNGYLSFEEFCFILCSLIKGS-AEDKLKFIFSMHDVNGNGILPKEEFSRMLRS 871

  Fly   106 LRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
            .|:|.:.|..:.|:..::.|..||.|....::.:|:|
Frog   872 FRNVSSFLSNEKTENVIESMFNEAGISNKKELAWEDF 908

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cam	NP_001246276.1	PTZ00184	1..149	CDD:185504	41/167 (25%)
duox2	XP_017947900.2	dual_peroxidase_like	29..581	CDD:188652
		FRQ1	726..918	CDD:227455	41/167 (25%)
		PLN02292	1056..>1376	CDD:215165
		NOX_Duox_like_FAD_NADP	1244..1517	CDD:99783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910