DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha36-2 and atp6v1d

DIOPT Version :9

Sequence 1:	NP_610753.1	Gene:	Vha36-2 / 36328	FlyBaseID:	FBgn0033706	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001161426.1	Gene:	atp6v1d / 393935	ZFINID:	ZDB-GENE-040426-727	Length:	248	Species:	Danio rerio

Alignment Length:	258	Identity:	97/258 - (37%)
Similarity:	141/258 - (54%)	Gaps:	16/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKRDILPIFPSRANSVIMKQRVLAARRGVGLLKRKRDAIDMKLRE-LRRIRFDQDMHGDEAMRN 64
            |:.::.:.|||||....|||.|:..|:.|..|||:|.||:.|:.|: ||:|...:.:.| |.||.
Zfish     1 MSGKERIDIFPSRMAQTIMKARLKGAQTGRSLLKKKSDALSMRFRQILRKIIETKTLMG-EVMRE 64

  Fly    65 AIFSMAKANLLGADFKPQMVSRSHVATVSLRRTEIKIVGVKLNTLELETKGVGAFPLAGLSCGGM 129
            |.||:|:|.....||...::...:.|.|.:|..:..:.||.|...|...:|..::.|.||:.||.
Zfish    65 AAFSLAEAKFAAGDFSTTVIQNVNKAQVKVRAKKDNVAGVTLPVFEHYQEGGDSYELTGLARGGE 129

  Fly   130 QVSRIRDSYTKALKALVEFASLEYQVRMLEAASLQTNMRVNALEHVVIPILQNTYNYICGELEEF 194
            |:||::.:|.||::.|||.|||:.....|:.|...||.||||:|||:||.::.|..||..||:|.
Zfish   130 QLSRLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLTYIITELDER 194

  Fly   195 EREDFYRLKRSQAKQLEAKMAFTELIKTKNMTDEELETYIKRNINQTRPPAADTPFDQEQFEE 257
            |||:|||||:.|.|              |....|..|..|.:.:....|.|..|....|:.:|
Zfish   195 EREEFYRLKKIQEK--------------KKQLRERTEKEIAKRLAALGPIAEPTNMLTEEADE 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha36-2	NP_610753.1	ATP-synt_D	18..206	CDD:280060	80/188 (43%)
		PEHE	<253..>294	CDD:291924	2/5 (40%)
		DUF4628	<281..>373	CDD:292069
atp6v1d	NP_001161426.1	ATP-synt_D	17..206	CDD:280060	80/189 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1394
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1313938at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101069
Panther	1	1.100	-	-	O	PTHR11671
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.780