Protein Alignment Rnf149 and RNF149

DIOPT Version :10

• Sequence 1: NP_001418215.1
• Gene: Rnf149 / 363222
• RGDID: 1308460
• Length: 394
• Species: Rattus norvegicus
• Sequence 2: XP_005263977.1
• Gene: RNF149 / 284996
• HGNCID: 23137
• Length: 428
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 301/388 - (77%)
• Similarity: 329/388 - (84%)
• Gaps: 8/388 - (2%)

  Rat     1 MAARRRPAAGVGARD--ALAVLALALCAPGVGGGALEWYSATVSIEYVDPQSNLTVWSVTESGRF 63
            ||.|||.|: ||||.  |||:||||||.||..|.||||:||.|:|||||||:|||||||:|||||
Human     1 MAWRRREAS-VGARGVLALALLALALCVPGARGRALEWFSAVVNIEYVDPQTNLTVWSVSESGRF 64

  Rat    64 GDSSLREERQGLVGVPRAP-ADAEGCAPDTRFVA--PGALGNAPWVALVARGGCTFKDKVLAAAR 125
            ||||.:|...||||||.|| .|.|||||||||..  ||..|.|||||||||||||||||||.|||
Human    65 GDSSPKEGAHGLVGVPWAPGGDLEGCAPDTRFFVPEPGGRGAAPWVALVARGGCTFKDKVLVAAR 129

  Rat   126 RNASAVVVYNQERYGNATEPMSHAGTGSIVVIMISYPKGREISDLVQKGIPVKMRIEIGTRHMQE 190
            |||||||:||:|||||.|.||||||||:||||||||||||||.:||||||||.|.|.:||||:||
Human   130 RNASAVVLYNEERYGNITLPMSHAGTGNIVVIMISYPKGREILELVQKGIPVTMTIGVGTRHVQE 194

  Rat   191 FISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQNHRKETKKVIGQLPLHTVKHGE 255
            |||||||||||||||||||||||||||||||||||||||.|||:||||||||||||.||||||||
Human   195 FISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQIGSQSHRKETKKVIGQLLLHTVKHGE 259

  Rat   256 KGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPE 320
            |||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||:|.
Human   260 KGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPG 324

  Rat   321 DAQDLPIPEAAPGSVSVGNLSVTVQDEERS-ESNLPSSSSSEFGPH-RPCLKEDAEEDTALLG 381
            |.|::|.||:.||.....|||:.:.|::.| :|:.||:|.:|..|. .|..|.||.|:|||||
Human   325 DVQEMPAPESPPGRDPAANLSLALPDDDGSDDSSPPSASPAESEPQCDPSFKGDAGENTALLG 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf149	NP_001418215.1	PA_GRAIL_like	45..181	CDD:239037	111/138 (80%)
		RING-H2_RNF149	264..311	CDD:438455	45/46 (98%)
RNF149	XP_005263977.1	PA_GRAIL_like	43..185	CDD:239037	113/141 (80%)
		RING-H2_RNF149	268..315	CDD:438455	45/46 (98%)