DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t3 and LUT1

DIOPT Version :9

Sequence 1:	NP_610745.1	Gene:	Cyp6t3 / 36318	FlyBaseID:	FBgn0033697	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	110/501 - (21%)
Similarity:	189/501 - (37%)	Gaps:	107/501 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LGQLLFLRI-----SFGDLFRQLYADPRNGQAKIVGFFIFQTPAL---MVRDPELIRQVLIKNFN 100
            ||..|||.:     .:|.::| |.|.|||       |.|...||:   ::|:.....:.|:...:
plant    93 LGGALFLPLYKWMNEYGPIYR-LAAGPRN-------FVIVSDPAIAKHVLRNYPKYAKGLVAEVS 149

  Fly   101 NFLNRFESADAGDPMGALTLPLAKYHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNR 165
            .||.....|.|..|:            |            :.|.|.|:.|......|.:.:.:..
plant   150 EFLFGSGFAIAEGPL------------W------------TARRRAVVPSLHRRYLSVIVERVFC 190

  Fly   166 KLGDRL-ERVLPL----------GRMCQLYTTDVTGNLFYSLNVGGLRRGR---SELITKTKELF 216
            |..:|| |::.|.          .:..|: |.||.|...::.|...|....   ..:.|..||
plant   191 KCAERLVEKLQPYAEDGSAVNMEAKFSQM-TLDVIGLSLFNYNFDSLTTDSPVIEAVYTALKE-- 252

  Fly   217 NTNPRKVLDFMSVFFLPKW-----TGVLKPKVFTEDYARYMRHLVDDHHEPTK------GDLINQ 270
                   .:..|...||.|     ..::..:|..|.....:|..|:|.....|      |:.||.
plant   253 -------AELRSTDLLPYWKIDALCKIVPRQVKAEKAVTLIRETVEDLIAKCKEIVEREGERIND 310

  Fly   271 -----------LQHFQLSRSSNHYSQHPDFVASQAGIILLAGFETSSALMGFTLYELAKAPDIQE 324
                       |:....||......|..|.:.|    :|:||.||:.:::.:|||.|:|......
plant   311 EEYVNDADPSILRFLLASREEVSSVQLRDDLLS----MLVAGHETTGSVLTWTLYLLSKNSSALR 371

  Fly   325 RLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYP-AAAFVNRECTSSASEGFSLQPHVDF 388
            :.:.|: :..:.....:::.:..|.|:.....|::|||| ....:.|........|       ::
plant   372 KAQEEV-DRVLEGRNPAFEDIKELKYITRCINESMRLYPHPPVLIRRAQVPDILPG-------NY 428

  Fly   389 IVPPGMPAYISILGLHRDERFWPEPCVFDPERF---GPERSRHIHPMTYIPFGAGPHGCIGSRLG 450
            .|..|....||:..:||....|.:...|.||||   |...:.......:|||..||..|:|.:..
plant   429 KVNTGQDIMISVYNIHRSSEVWEKAEEFLPERFDIDGAIPNETNTDFKFIPFSGGPRKCVGDQFA 493

  Fly   451 VLQLKLGIVHILKQYWVETC-ERTVSEIRFNPKSFMLESENEIYLR 495
            :::..:.:...|::..||.. ::|:|    ......:.:.|.:|::
plant   494 LMEAIVALAVFLQRLNVELVPDQTIS----MTTGATIHTTNGLYMK 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	108/490 (22%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	110/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010