DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t3 and cyp2j20

DIOPT Version :9

Sequence 1:	NP_610745.1	Gene:	Cyp6t3 / 36318	FlyBaseID:	FBgn0033697	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_001337781.3	Gene:	cyp2j20 / 797309	ZFINID:	ZDB-GENE-041210-324	Length:	496	Species:	Danio rerio

Alignment Length:	507	Identity:	96/507 - (18%)
Similarity:	199/507 - (39%)	Gaps:	100/507 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLIWLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWS-P-MGNLGQL----LFLRISFGDLFRQ 60
            :||::.:..:::         |:.:::...:.||..|| | :|::..:    |.|::|   .|.:
Zfish    15 ILIFVCVFLLLS---------DFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKLHLQLS---EFAE 67

  Fly    61 LYADPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDPMGALTLPLAKY 125
            .|       .||....:|....:::....|:::|..:..:|..:|.......|.:|...|..:..
Zfish    68 KY-------GKIFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDKGLVASSG 125

  Fly   126 HHWKESRQ-CMSQLFTSGRMRDVMYSQMLDVASDLEQ-YLNRKLGDRL-----ERVLPLGRMCQL 183
            :.||:.|: .:|.|...|     :..:.|:.:.:||. :||..:.:..     .|:|....:..:
Zfish   126 YKWKQQRRFALSTLRNFG-----LGKKNLEPSINLESGFLNEAISNEQGQPFDPRLLLNNAVSNV 185

  Fly   184 YTTDVTGNLF-YS--------LNV-------GGLRRGRSELITKTKELFNTNP--RKVLDFMSVF 230
            ....|.||.| ||        .|:       ||:          ..:|:|..|  .::|......
Zfish   186 ICALVFGNRFDYSDHKFQTLLKNINETVHLEGGI----------CAQLYNMLPWLMRLLPGPHKR 240

  Fly   231 FLPKWTGVLKPKVFTEDYARYMRHLVDDH---HEPTKGDLINQLQHFQLSRSSNHYSQHPDFVAS 292
            .:..|..:::          ::...|::|   |:|     :|...:  :....:...:|.|..|:
Zfish   241 IIALWGKLIE----------FVGEKVNEHKVDHDP-----LNPRDY--IDCFLDEMEKHKDDTAA 288

  Fly   293 QAGI---------ILLAGFETSSALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTL 348
            ...:         :.:||.||:|..:.:.|..:.|.|:||.:::.|:......:...|......:
Zfish   289 GFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGSRQPSVSDRDNM 353

  Fly   349 PYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEP 413
            ||...|..|..|:   ...:......:.||...::   .:.:|.|.....::..:..||..|..|
Zfish   354 PYTNAVIHEIQRM---GNIIPINLARTTSEDTQIE---KYSIPKGTMVTSNLTSVLFDESEWETP 412

  Fly   414 CVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQY 465
            ..|:|..|.....:......::||..|...|:|.:|..::|.|....:|:::
Zfish   413 HSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRF 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	93/475 (20%)
cyp2j20	XP_001337781.3	p450	38..492	CDD:278495	93/475 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010