Protein Alignment Cyp6t3 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 518
• Identity: 148/518 - (28%)
• Similarity: 243/518 - (46%)
• Gaps: 62/518 - (11%)

  Fly     5 WLLLLTIVTLNFWLRHKYDY--FRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYADPRN 67
            |:||:|.:.. |::...|.:  |:..|||  .|......||:       |::.|...:...|...
Mouse    12 WVLLVTSLVF-FYIYGTYSHGLFKKLGIP--GPKPLPLFGNI-------INYLDGMWKFDDDCYK 66

  Fly    68 GQAKIVGFFIFQTPALMVRDPELIRQVLIKN-FNNFLNRFESADAGDPMGAL--TLPLAKYHHWK 129
            ...||.||:....|.|.:.|||:|:.||:|. ::.|.||....    |:|.|  ::.:::...||
Mouse    67 KYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFG----PVGFLKKSITISEDEEWK 127

  Fly   130 ESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLYTTDVTGNLFY 194
            ..|..:|..|||.:::: |:..|......|.:.|.|:  :..|..:.:..:...|:.||......
Mouse   128 RLRTLLSPTFTSSKLKE-MFPIMRQYGDILVRNLRRE--EEKEEPINMKDIFGAYSMDVITGTSC 189

  Fly   195 SLNVGGLRRGRSELITKTKELFNTNPRKVLDF-------MSVFFLPKWTGV---LKPKVFTEDYA 249
            .:|:..|...:...:.|.|        |:|.|       :||...|..|.:   |...:|.....
Mouse   190 GVNIDSLNNPQDPFVQKIK--------KILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIFPRQSM 246

  Fly   250 RYMRHLVD-------DHHEPTKGDLINQLQHFQLSRSSNHYSQHPDF-VASQAGIILLAGFETSS 306
            .:.:..|.       |:::..:.|.:..:.:.|.|:.........|. :|:|..|.:..|::.:|
Mouse   247 NFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGGYDGTS 311

  Fly   307 ALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRE 371
            ..:.|.:||||..||:|::|:.|:..|..:.|.::||.||.:.||.||..|:|||||..:.::|
Mouse   312 TSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDR- 375

  Fly   372 CTSSASEGFS---LQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMT 433
                    ||   ::.|..|| |.|....|.|..||||..:||||..|.||||..|...:|.|..
Mouse   376 --------FSKKDVEIHGVFI-PKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYI 431

  Fly   434 YIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNPKSFMLESENEIYLRF 496
            |:|||.||..|||.|..::.:||.:..:|:.:.|:.||.|...::.: :..:...|..|.|:|
Mouse   432 YMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKIS-RQPIFRPEKPIILKF 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	129/448 (29%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	130/450 (29%)