Protein Alignment Cyp6t3 and Cyp6a8

DIOPT Version :9

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 166/533 - (31%)
• Similarity: 270/533 - (50%)
• Gaps: 69/533 - (12%)

  Fly     1 MLLIWLL------LLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFR 59
            |.|.::|      ||.|:|  :::..|..||:.||||.:.|.  ...||:.:|...: :..::|:
  Fly     1 MALTYILFQVAVALLAILT--YYIHRKLTYFKRRGIPFVAPH--LIRGNMEELQKTK-NIHEIFQ 60

  Fly    60 QLYADPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNR---FESADAGDPMGA--LT 119
            ..|...|..:|..||||.||:||..|.|.||.:|:|||:|:||.|:   :...|  ||:.|  ..
  Fly    61 DHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKD--DPISAHLFN 123

  Fly   120 LPLAKYHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLY 184
            |..|:   |:..|..:|..||||:|: :||..::.||::....::.|:..  ..||.:..:...:
  Fly   124 LDGAQ---WRLLRNKLSSTFTSGKMK-LMYPTVVSVANEFMTVMHEKVPK--NSVLEIRDLVARF 182

  Fly   185 TTDVTGNLFYSLNVGGLRRGRSELITKTKELFNTNPRKVLD---------FMSVFFLPKWT---G 237
            |.||.|...:.:....||..::|.:...|       |.::|         ||..:  ||..   |
  Fly   183 TVDVIGTCAFGIQCNSLRDEKAEFLYFGK-------RSLVDKRHGTLLNGFMRSY--PKLARKLG 238

  Fly   238 VLK--PKVFTEDYARYMRHLV----DDHHEPTKGDLINQLQHFQLSRSSNHYSQHPDF------- 289
            :::  |.: .|.|:|.:...|    .:|.:  :.|.::.|  .:|........::.|.
  Fly   239 MVRTAPHI-QEFYSRIVTETVAVREKEHIK--RNDFMDML--IELKNQKEMTLENGDVVRGLTME 298

  Fly   290 -VASQAGIILLAGFETSSALMGFTLYELAKAPDIQERLRSELREAFIS-TATLSYDTLMTLPYLK 352
             |.:||.:..:|||||||:.|||.||||||.||||:::|:|:.|.... ....:|:....|.||.
  Fly   299 EVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLN 363

  Fly   353 MVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFD 417
            .|..|.||||.....::|    .|::.:.:..|.:|::..|....|....:|.|...:|||..|.
  Fly   364 QVLDETLRLYTIVPNLDR----MAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFR 424

  Fly   418 PERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNPK 482
            ||||.||.|.....:.::|||.||..|||.|.|.:|.::|:..:::.:...||.:|.:.:.::||
  Fly   425 PERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPK 489

  Fly   483 SFMLESENEIYLR 495
            ||:|..::.|||:
  Fly   490 SFVLGVKDGIYLK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	148/483 (31%)
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	152/493 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461079
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900