Protein Alignment Cyp6t3 and Cyp6a2

DIOPT Version :9

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 152/517 - (29%)
• Similarity: 255/517 - (49%)
• Gaps: 37/517 - (7%)

  Fly     1 MLLIWLLLLTIVTLNFWLRHK-YDYFRSRGIPHLPPSSWSPM-GNLGQLLFLRISFGDLFRQLYA 63
            |.::..||:.|.:|..:|.|: ::|:..||:||..|   .|: ||:......|: ..|.|...|.
  Fly     1 MFVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAP---HPLYGNMVGFRKNRV-MHDFFYDYYN 61

  Fly    64 DPRNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDPMGALTLPLAKY--- 125
            ..|......|||:....||..:.|.:|.:.:|||:|:||.:|.:..:..|.      ||.::
  Fly    62 KYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDD------PLTQHLFN 120

  Fly   126 ---HHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYLNRKL-GDRLERVLPLGRMCQLYTT 186
               ..||:.||.::..||||:|: .|:..::.|:.:..:.:..:: ..:...||.:..:...:||
  Fly   121 LDGKKWKDMRQRLTPTFTSGKMK-FMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTT 184

  Fly   187 DVTGNLFYSLNVGGLRRGRSELITKTKELFNTNPRKVLDFMSVFFLPKWTGVLKPKVFTEDYARY 251
            ||.|...:.:....||...|:..|..:::|.......|..|.||..||....|:.::..||..::
  Fly   185 DVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQF 249

  Fly   252 MRHLVDD------HHEPTKGDLINQL----QHFQLSRSSNHYSQHPDF--VASQAGIILLAGFET 304
            ...||:|      .....:.|.:|.|    |..:::..:....:..|.  :|:|..:..:|||||
  Fly   250 FMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFET 314

  Fly   305 SSALMGFTLYELAKAPDIQERLRSELREAF-ISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFV 368
            ||:.|.:.|||||:..|||:|||:|::... .....|:|:::..:.||..|..|.||||.....:
  Fly   315 SSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHL 379

  Fly   369 NRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMT 433
            .|:    |...:.:..|...::..|....|.....||||..:|.|..||||||.||:......:.
  Fly   380 ERK----ALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVE 440

  Fly   434 YIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNPKSFMLESENEIYLR 495
            ::|||.||..|||.|.|.:|.::|:..|:.::.|..|:.|...::::|.|.:|.:...||||
  Fly   441 WLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	135/472 (29%)
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	138/480 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461077
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900