Protein Alignment Cyp6t3 and Cyp4a12a

DIOPT Version :10

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 517
• Identity: 115/517 - (22%)
• Similarity: 209/517 - (40%)
• Gaps: 69/517 - (13%)

  Fly     6 LLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYADPRNGQA 70
            ||||...|...:|..::....::..|. |||.|.    .|..:.......|:..::...|.....
Mouse    27 LLLLLFKTAQLYLHRQWLLSSTQQFPS-PPSHWL----FGHKILKDQDLQDILTRIKNFPSACPQ 86

  Fly    71 KIVGFFIFQTPALMVRDPELIRQVLIKN--FNNFLNRFESADAGDPMGALTLPLAKYHHWKESRQ 133
            .:.|..:    .:.|.||:.::.:|.::  ..|...||.:...|  .|.|.|   ....|.:.|:
Mouse    87 WLWGSKV----RIQVYDPDYMKLILGRSDPKANGSYRFLAPWIG--RGLLML---DGQTWFQHRR 142

  Fly   134 CMSQLFTSGRMR---DVMYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQLYTTDVTGNLFYS 195
            .::..|....::   ::|...:..:....||.:.:      :..|.:.|...|.|.|......:|
Mouse   143 MLTPAFHYDILKPYTEIMADSVRVMLDKWEQIVGQ------DSTLEIFRHITLMTLDTIMKCAFS 201

  Fly   196 LNVGGLRRGRS-----ELITKTKELFNTNPRKVLDFMSVFFLPKWTGVLKPKV------FTEDYA 249
             :.|.::..|.     :.:....:|..:..|.:.....:.:.....|......      .|:...
Mouse   202 -HEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSNGCKANSACKLAHDHTDQVI 265

  Fly   250 RYMRHLVDDHHEPTKGDLINQLQHFQL---SRSSNHYSQHPDFVASQAGIILLAGFETSSALMGF 311
            :..|..:.|..|..|.....:|....:   :|..|..|.....:.::....:..|.:|:::.:.:
Mouse   266 KSRRIQLQDEEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISW 330

  Fly   312 TLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSA 376
            ..|.||..|:.|:|.|.|::.......:::::.|..:||..|...||||:||....|:||.:|..
Mouse   331 IFYALATNPEHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPV 395

  Fly   377 S--EGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMTYIPFGA 439
            :  :|.||        |.|:...:|..|||.:...||.|.||||.||.|..|||.|  :::||..
Mouse   396 TFPDGRSL--------PKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSSRHSH--SFLPFSG 450

  Fly   440 GPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNP-------KSFMLESENEIYL 494
            |...|||.:..:.:||:.:...|.::          |:..:|       ...:|:|:|.|:|
Mouse   451 GARNCIGKQFAMNELKVAVALTLLRF----------ELLPDPTRVPIPIPRIVLKSKNGIHL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	99/452 (22%)
Cyp4a12a	NP_803125.2	CYP4B-like	70..503	CDD:410771	103/469 (22%)