Protein Alignment Cyp6t3 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 126/568 - (22%)
• Similarity: 209/568 - (36%)
• Gaps: 162/568 - (28%)

  Fly     1 MLLIWLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSW--------SPMGNLGQLLFLRISFGDL 57
            ::|.:|.|:.::.....|....|.|..      ||:.|        ...|:|.::    :|:...
Human    22 LVLGFLKLIHLLLRRQTLAKAMDKFPG------PPTHWLFGHALEIQETGSLDKV----VSWAHQ 76

  Fly    58 FRQLYADPR-NGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDP------- 114
            |.  ||.|. .||  .:||       |.:.:|:..:.|..:              |||
Human    77 FP--YAHPLWFGQ--FIGF-------LNIYEPDYAKAVYSR--------------GDPKAPDVYD 116

  Fly   115 -------MGALTLPLAKYHHWKESRQCMSQLFTSGRMRDVMYSQMLDVASDLEQYL------NRK 166
                   .|.|.|...|   |.:.|    :|.|.|...||           |:.|:      .|.
Human   117 FFLQWIGRGLLVLEGPK---WLQHR----KLLTPGFHYDV-----------LKPYVAVFTESTRI 163

  Fly   167 LGDRLERVLPLGRMCQLYTTDVTGNLFYSLNV----------GGLRRGR-SELITKTKELFNTNP 220
            :.|:.|.....|:...:: .|| |::  :||.          .||...| |.......:|.....
Human   164 MLDKWEEKAREGKSFDIF-CDV-GHM--ALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQ 224

  Fly   221 RKVLDFM----SVFFLPKWTGVLKPKVFTEDYARYMR--HLVDDHHEPTKGDLINQLQHFQLSRS 279
            ::::.|.    .:::|            |....|::|  .:..||.:....:....||..:: |.
Human   225 QRLVSFQYHNDFIYWL------------TPHGRRFLRACQVAHDHTDQVIRERKAALQDEKV-RK 276

  Fly   280 SNHYSQHPDF-------------------VASQAGIILLAGFETSSALMGFTLYELAKAPDIQER 325
            .....:|.||                   :.::....:..|.:|:::.:.:.||.:|..|:.|.|
Human   277 KIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHR 341

  Fly   326 LRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSAS--EGFSLQPHVDF 388
            .|.|:||.........:|.|..:.||.|...|:.||||....|.|:.:...:  :|.||
Human   342 CREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSL------ 400

  Fly   389 IVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQ 453
              |.|....:.|..|||:...||:|.|||..||..|.:...||..::||.|||..|||.:..:.:
Human   401 --PAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSE 463

  Fly   454 LKLGIVHILKQYWVETCERTVSEIRFNPK-------SFMLESENEIYL 494
            :|:.....|.::          |...:|.       ..:|.|:|..:|
Human   464 MKVVTAMCLLRF----------EFSLDPSRLPIKMPQLVLRSKNGFHL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t3	NP_610745.1	p450	34..486	CDD:299894	116/525 (22%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	119/541 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010